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Robert Vassar

1989–2025 年に発表

108
論文数
28,783
被引用数
73
h 指数
102
i10 指数

被引用数

Robert Vassar の年別被引用数1962 年: 被引用 1 件1989 年: 被引用 5 件1990 年: 被引用 9 件1991 年: 被引用 19 件1992 年: 被引用 36 件1993 年: 被引用 53 件1994 年: 被引用 70 件1995 年: 被引用 50 件1996 年: 被引用 78 件1997 年: 被引用 60 件1998 年: 被引用 71 件1999 年: 被引用 85 件2000 年: 被引用 155 件2001 年: 被引用 223 件2002 年: 被引用 234 件2003 年: 被引用 189 件2004 年: 被引用 264 件2005 年: 被引用 226 件2006 年: 被引用 265 件2007 年: 被引用 257 件2008 年: 被引用 282 件2009 年: 被引用 284 件2010 年: 被引用 335 件2011 年: 被引用 356 件2012 年: 被引用 377 件2013 年: 被引用 333 件2014 年: 被引用 402 件2015 年: 被引用 386 件2016 年: 被引用 453 件2017 年: 被引用 409 件2018 年: 被引用 377 件2019 年: 被引用 1,004 件2020 年: 被引用 1,055 件2021 年: 被引用 1,030 件2022 年: 被引用 848 件2023 年: 被引用 715 件2024 年: 被引用 1,038 件2025 年: 被引用 661 件2026 年: 被引用 22 件2027 年: 被引用 1 件1963〜1988 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 4,085 件、この内訳の 31.1%中国: 引用元論文 1,295 件、この内訳の 9.9%ドイツ: 引用元論文 815 件、この内訳の 6.2%イギリス: 引用元論文 701 件、この内訳の 5.3%日本: 引用元論文 513 件、この内訳の 3.9%インド: 引用元論文 435 件、この内訳の 3.3%イタリア: 引用元論文 423 件、この内訳の 3.2%韓国: 引用元論文 390 件、この内訳の 3%カナダ: 引用元論文 386 件、この内訳の 2.9%フランス: 引用元論文 338 件、この内訳の 2.6%スペイン: 引用元論文 308 件、この内訳の 2.4%オーストラリア: 引用元論文 298 件、この内訳の 2.3%
0%31.1%その他 23.9%

機関

分野

  • Medicine55.3%
  • Biochemistry, Genetics and Molecular Biology18.7%
  • Neuroscience18.3%
  • Computer Science3%
  • Immunology and Microbiology1.2%
  • Agricultural and Biological Sciences0.7%
  • その他2.8%

トピック

  • Alzheimer's disease research and treatments18.8%
  • Cholinesterase and Neurodegenerative Diseases5.9%
  • Neuroinflammation and Neurodegeneration Mechanisms5.1%
  • Computational Drug Discovery Methods5%
  • Neuroscience and Neuropharmacology Research2.6%
  • Tryptophan and brain disorders2.2%
  • その他60.4%

共著者

全論文

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  1. Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

    著者: Holly D. Oakley, Sarah L. Cole, Sreemathi Logan, Erika Maus, Pei Shao, Jeffery Craft, Angela Guillozet-Bongaarts, Masuo Ohno, John F. Disterhoft, Linda Van Eldik, R. Stephen Berry, Robert Vassar - Journal of Neuroscience 2006 被引用: 3,581

  2. The β-Secretase BACE1 in Alzheimer’s Disease

    著者: Harald Hampel, Robert Vassar, Bart De Strooper, John Hardy, Michael Willem, Neeraj Singh, John Zhou, Riqiang Yan, Eugeen Vanmechelen, Ann De Vos, Robert Nisticò, Massimo Corbo, Bruno P. Imbimbo, Johannes Streffer, Iryna Voytyuk, Maarten Timmers, Amir Abbas Tahami Monfared, Michael C. Irizarry, Bruce Albala, Akihiko Koyama, Naoto Watanabe, Teiji Kimura, Lisa Yarenis, Simone Lista, Lynn D. Kramer, Andrea Vergallo - Biological Psychiatry 2020 被引用: 666

  3. The gut microbiome in Alzheimer’s disease: what we know and what remains to be explored

    著者: Sidhanth Chandra, Sangram S. Sisodia, Robert Vassar - Molecular Neurodegeneration 2023 被引用: 265

  4. APP mouse models for Alzheimer's disease preclinical studies

    著者: Hiroki Sasaguri, Per Nilsson, Shoko Hashimoto, Kenichi Nagata, Takashi Saito, Bart De Strooper, John Hardy, Robert Vassar, Bengt Winblad, Takaomi C. Saido - The EMBO Journal 2017 被引用: 785

  5. β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

    著者: Robert Vassar, Brian D. Bennett, Safura Babu‐Khan, Steve Kahn, Elizabeth A. Mendiaz, Paul Denis, David B. Teplow, Sandra L. Ross, Patricia Amarante, Richard Loeloff, Yi Luo, Seth Fisher, Janis Fuller, Steven Edenson, Jackson Lile, Mark A. Jarosinski, Anja Leona Biere, Eileen Curran, Teresa L. Burgess, Jean-Claude Louis, Frank M. Collins, James Treanor, Gary N. Rogers, Martin Citron - Science 1999 被引用: 3,836

  6. The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease

    著者: Ji‐Yeun Hur, Georgia Frost, Xianzhong Wu, Christina J. Crump, Si Pan, Eitan Wong, Marilia Barros, Thomas Li, Pengju Nie, Yujia Zhai, Jen Chyong Wang, Julia TCW, Lei Guo, Andrew McKenzie, Ming Chen, Xianxiao Zhou, Minghui Wang, Yotam Sagi, Alan E. Renton, Bianca Esposito, Yong Kim, Katherine R. Sadleir, Ivy Trinh, Robert A. Rissman, Robert Vassar, Bin Zhang, Douglas S. Johnson, Eliezer Masliah, Paul Greengard, Alison Goate, Yue‐Ming Li - Nature 2020 被引用: 394

  7. Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation

    著者: William A. Eimer, Robert Vassar - Molecular Neurodegeneration 2013 被引用: 414

  8. AD-BERT: Using pre-trained language model to predict the progression from mild cognitive impairment to Alzheimer's disease

    著者: Chengsheng Mao, Jie Xu, Luke V. Rasmussen, Yikuan Li, Prakash Adekkanattu, Jennifer A. Pacheco, Borna Bonakdarpour, Robert Vassar, Li Shen, Guoqian Jiang, Fei Wang, Jyotishman Pathak, Yuan Luo - Journal of Biomedical Informatics, J. Biomed. Informatics 2023 被引用: 63

  9. The Alzheimer's disease Beta-secretase enzyme, BACE1

    著者: Sarah L. Cole, Robert Vassar - Molecular Neurodegeneration 2007 被引用: 545

  10. Targeting the β secretase BACE1 for Alzheimer's disease therapy

    著者: Riqiang Yan, Robert Vassar - The Lancet Neurology 2014 被引用: 624

  11. The case for low-level BACE1 inhibition for the prevention of Alzheimer disease

    著者: Eric McDade, Iryna Voytyuk, Paul Aisen, Randall J. Bateman, María C. Carrillo, Bart De Strooper, Christian Haass, Eric M. Reiman, Reisa A. Sperling, Pierre N. Tariot, Riqiang Yan, Colin L. Masters, Robert Vassar, Stefan F. Lichtenthaler - Nature Reviews Neurology 2021 被引用: 135

  12. The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis

    著者: Jie Zhao, Tracy O’Connor, Robert Vassar - Journal of Neuroinflammation 2011 被引用: 360

  13. Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer’s disease

    著者: Katherine R. Sadleir, Patty C. Kandalepas, Virginie Buggia-Prévot, Daniel A. Nicholson, Gopal Thinakaran, Robert Vassar - Acta Neuropathologica 2016 被引用: 296

  14. Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer’s disease model mice

    著者: Andrew Octavian Sasmita, Constanze Depp, T. I. Nazarenko, Ting Sun, Sophie B. Siems, Erinne Cherisse Ong, Yakum Bertrand Nkeh, Carolin Böhler, Xuan Yu, Bastian Bues, Lisa Evangelista, Shuying Mao, Bárbara Morgado, Zoe Y. Wu, Torben Ruhwedel, Swati Subramanian, Friederike Börensen, Katharina Overhoff, Lena Spieth, Stefan A. Berghoff, Katherine R. Sadleir, Robert Vassar, Simone Eggert, Sandra Goebbels, Takashi Saito, Takaomi C. Saido, Gesine Saher, Wiebke Möbius, Gonçalo Castelo‐Branco, Hans‐Wolfgang Klafki, Oliver Wirths, Jens Wiltfang, Sarah Jäkel, Riqiang Yan, Klaus‐Armin Nave - Nature Neuroscience 2024 被引用: 101

  15. The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms

    著者: Sidhanth Chandra, Antonio Di Meco, Hemraj B. Dodiya, Jelena Popović, Leah K. Cuddy, Ian Q. Weigle, Xiaoqiong Zhang, Katherine R. Sadleir, Sangram S. Sisodia, Robert Vassar - Molecular Neurodegeneration 2023 被引用: 56

  16. The β-Secretase Enzyme BACE in Health and Alzheimer's Disease: Regulation, Cell Biology, Function, and Therapeutic Potential

    著者: Robert Vassar, Dora M. Kovacs, Riqiang Yan, Philip C. Wong - Journal of Neuroscience 2009 被引用: 576

  17. Endothelial BACE1 Impairs Cerebral Small Vessels via Tight Junctions and eNOS

    著者: Haoyue Zhou, Feng Gao, Xiaoli Yang, Tingting Lin, Zhenxing Li, Qiong Wang, Yang Yao, Lei Li, Xinxin Ding, Kaibin Shi, Qiang Liu, Hong Bao, Zhenyu Long, Zujun Wu, Robert Vassar, Xin Cheng, Rena Li, Yong Shen - Circulation Research 2022 被引用: 76

  18. The secretases: enzymes with therapeutic potential in Alzheimer disease

    著者: Bart De Strooper, Robert Vassar, Todd E. Golde - Nature Reviews Neurology 2010 被引用: 787

  19. BACE1 inhibitor drugs in clinical trials for Alzheimer’s disease

    著者: Robert Vassar - Alzheimer s Research & Therapy 2014 被引用: 416

  20. Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1

    著者: Masuo Ohno, Lei Chang, Wilbur Tseng, Holly D. Oakley, Martin Citron, William L. Klein, Robert Vassar, John F. Disterhoft - European Journal of Neuroscience 2006 被引用: 303

  21. The Alzheimer’s β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques

    著者: Patty C. Kandalepas, Katherine R. Sadleir, William A. Eimer, Jie Zhao, Daniel A. Nicholson, Robert Vassar - Acta Neuropathologica 2013 被引用: 241

  22. Inhibition of Glycogen Synthase Kinase-3 Ameliorates β-Amyloid Pathology and Restores Lysosomal Acidification and Mammalian Target of Rapamycin Activity in the Alzheimer Disease Mouse Model

    著者: Limor Avrahami, Dorit Farfara, Maya Shaham-Kol, Robert Vassar, Dan Frenkel, Hagit Eldar-Finkelman - Journal of Biological Chemistry 2012 被引用: 227

  23. A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease

    著者: Altea Rocchi, Soh Yamamoto, Tabitha C. Ting, Yuying Fan, Katherine R. Sadleir, Yigang Wang, Weiran Zhang, Sui Huang, Beth Levine, Robert Vassar, Congcong He - PLoS Genetics 2017 被引用: 162

  24. Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models

    著者: Fan Liao, Tony Zhang, Hong Jiang, Katheryn B. Lefton, Grace O. Robinson, Robert Vassar, Patrick M. Sullivan, David M. Holtzman - Acta Neuropathologica Communications 2015 被引用: 78