Roberto Zoncu
2002–2025 年に発表
- 66
- 論文数
- 27,591
- 被引用数
- 48
- h 指数
- 60
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine46.4%
- Biochemistry, Genetics and Molecular Biology43%
- Neuroscience3.4%
- Immunology and Microbiology3.1%
- Agricultural and Biological Sciences0.8%
- Nursing0.7%
- その他2.6%
トピック
- Autophagy in Disease and Therapy6.9%
- Ferroptosis and cancer prognosis6.4%
- Cellular transport and secretion3.4%
- RNA modifications and cancer3.3%
- PI3K/AKT/mTOR signaling in cancer3.1%
- Cancer, Lipids, and Metabolism2.9%
- その他74%
共著者
- Rushika M. Perera16
- Derek Toomre13
- David M. Sabatini12
- Daniel K. Nomura8
- Guillermo Ayala8
- James H. Hurley7
- María Elena Díaz7
- Rafael Sebastián7
- Alejo Efeyan6
- Chun-Yan Lim6
- Hijai R. Shin6
- Pietro De Camilli6
- Rosalie Lawrence6
- Liron Bar‐Peled5
- Oliver B. Davis5
- James A. Olzmann4
- Y. Rose Citron4
- Aakriti Jain3
- Ashley Thelen3
- Brian M. Castellano3
- Charles A. Berdan3
- Dojin Kim3
- Douglas F. Covey3
- Ester Díaz3
全論文
- The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
著者: Kirill Bersuker, Joseph M. Hendricks, Zhipeng Li, Leslie Magtanong, Breanna Ford, Peter Tang, Melissa A. Roberts, Bingqi Tong, Thomas J. Maimone, Roberto Zoncu, Michael C. Bassik, Daniel K. Nomura, Scott J. Dixon, James A. Olzmann - Nature 2019 被引用: 3,681
- A lysosome‐to‐nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
著者: Carmine Settembre, Roberto Zoncu, Diego L. Medina, Francesco Vetrini, Serkan Erdin, SerpilUckac Erdin, Tuong Huynh, Mathieu Ferron, Gérard Karsenty, Michel Vellard, Valeria Facchinetti, David M. Sabatini, Andrea Ballabio - The EMBO Journal 2012 被引用: 1,920
- The lysosome as a cellular centre for signalling, metabolism and quality control
著者: Rosalie Lawrence, Roberto Zoncu - Nature Cell Biology 2018 被引用: 914
- Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
著者: Yasemin Sancak, Liron Bar‐Peled, Roberto Zoncu, Andrew L. Markhard, Shigeyuki Nada, David M. Sabatini - Cell 2010 被引用: 2,478
- mTOR: from growth signal integration to cancer, diabetes and ageing
著者: Roberto Zoncu, Alejo Efeyan, David M. Sabatini - Nature Reviews Molecular Cell Biology 2010 被引用: 3,945
- DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy
著者: Truc B. Nguyen, Sharon M. Louie, Joseph R. Daniele, Quân Tran, Andrew Dillin, Roberto Zoncu, Daniel K. Nomura, James A. Olzmann - Developmental Cell 2017 被引用: 613
- The Lysosome as a Regulatory Hub
著者: Rushika M. Perera, Roberto Zoncu - Annual Review of Cell and Developmental Biology 2016 被引用: 653
- mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H + -ATPase
著者: Roberto Zoncu, Liron Bar‐Peled, Alejo Efeyan, Shuyu Wang, Yasemin Sancak, David M. Sabatini - Science 2011 被引用: 1,633
- Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism
著者: Rushika M. Perera, Svetlana Stoykova, Brandon Nicolay, Kenneth N. Ross, Julien Fitamant, Myriam Boukhali, Justine Lengrand, Vikram Deshpande, Martin K. Selig, Cristina R. Ferrone, Jeff Settleman, Gregory Stephanopoulos, Nicholas J. Dyson, Roberto Zoncu, Sridhar Ramaswamy, Wilhelm Haas, Nabeel Bardeesy - Nature 2015 被引用: 807
- Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex
著者: Brian M. Castellano, Ashley Thelen, Ofer Moldavski, McKenna Feltes, Reini E.N. van der Welle, Laurel Mydock‐McGrane, Xuntian Jiang, Robert J. van Eijkeren, Oliver B. Davis, Sharon M. Louie, Rushika M. Perera, Douglas F. Covey, Daniel K. Nomura, Daniel S. Ory, Roberto Zoncu - Science 2017 被引用: 589
- The molecular basis of nutrient sensing and signalling by mTORC1 in metabolism regulation and disease
著者: Claire Goul, Roberta Peruzzo, Roberto Zoncu - Nature Reviews Molecular Cell Biology 2023 被引用: 236
- ER–lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann–Pick type C
著者: Chun-Yan Lim, Oliver B. Davis, Hijai R. Shin, Zuopeng Zhang, Charles A. Berdan, Xuntian Jiang, Jessica L. Counihan, Daniel Ory, Daniel K. Nomura, Roberto Zoncu - Nature Cell Biology 2019 被引用: 318
- Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.
著者: Shuyu Wang, Zhi-Yang Tsun, Rachel L. Wolfson, Kuang Shen, Gregory A. Wyant, Molly Plovanich, Elizabeth D. Yuan, Tony D. Jones, Lynne Chantranupong, William C. Comb, Timothy C. Wang, Liron Bar‐Peled, Roberto Zoncu, Christoph Straub, Choah Kim, Jiwon V. Park, Bernardo L. Sabatini, David M. Sabatini - 2015 被引用: 823
- NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C
著者: Oliver B. Davis, Hijai R. Shin, Chun-Yan Lim, Emma Wu, Matthew A. Kukurugya, Claire Maher, Rushika M. Perera, M. Paulina Ordoñez, Roberto Zoncu - Developmental Cell 2020 被引用: 201
- Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1
著者: Hijai R. Shin, Y. Rose Citron, Lei Wang, Laura Tribouillard, Claire S. Goul, Robin Stipp, Yusuke Sugasawa, Aakriti Jain, Nolwenn Samson, Chun-Yan Lim, Oliver B. Davis, David Castaneda-Carpio, Mingxing Qian, Daniel K. Nomura, Rushika M. Perera, Eunyong Park, Douglas F. Covey, Mathieu Laplante, Alex S. Evers, Roberto Zoncu - Science 2022 被引用: 132
- Emerging Roles for the Lysosome in Lipid Metabolism
著者: Ashley Thelen, Roberto Zoncu - Trends in Cell Biology 2017 被引用: 275
- Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1
著者: Liron Bar‐Peled, Lawrence D. Schweitzer, Roberto Zoncu, David M. Sabatini - Cell 2012 被引用: 913
- Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness
著者: Pekka Katajisto, Julia Döhla, Christine L. Chaffer, Nalle Pentinmikko, Nemanja D. Marjanovic, Sharif Iqbal, Roberto Zoncu, Walter W. Chen, Robert A. Weinberg, David M. Sabatini - Science 2015 被引用: 559
- The Folliculin Tumor Suppressor Is a GAP for the RagC/D GTPases That Signal Amino Acid Levels to mTORC1
著者: Zhi-Yang Tsun, Liron Bar‐Peled, Lynne Chantranupong, Roberto Zoncu, Timothy C. Wang, Choah Kim, Eric Spooner, David M. Sabatini - Molecular Cell 2013 被引用: 545
- Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival
著者: Alejo Efeyan, Roberto Zoncu, Steven H. Chang, Iwona Gumper, Harriet Snitkin, Rachel L. Wolfson, Oktay Kirak, David D. Sabatini, David M. Sabatini - Nature 2012 被引用: 451
- Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition
著者: Clive Yik‐Sham Chung, Hijai R. Shin, Charles A. Berdan, Breanna Ford, Carl C. Ward, James A. Olzmann, Roberto Zoncu, Daniel K. Nomura - Nature Chemical Biology 2019 被引用: 185
- Built to last: lysosome remodeling and repair in health and disease
著者: Roberto Zoncu, Rushika M. Perera - Trends in Cell Biology 2022 被引用: 79
- Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex
著者: Rosalie Lawrence, Simon A. Fromm, Yangxue Fu, Adam L. Yokom, Dojin Kim, Ashley Thelen, Lindsey N. Young, Chun-Yan Lim, Avi J. Samelson, James H. Hurley, Roberto Zoncu - Science 2019 被引用: 180
- The lysosome as a command-and-control center for cellular metabolism
著者: Chun-Yan Lim, Roberto Zoncu - The Journal of Cell Biology 2016 被引用: 296
