Shoukat Dedhar
1987–2025 年に発表
- 137
- 論文数
- 31,170
- 被引用数
- 100
- h 指数
- 133
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology46.7%
- Medicine40.6%
- Neuroscience3.9%
- Immunology and Microbiology2.8%
- Engineering2.4%
- Agricultural and Biological Sciences1.2%
- その他2.4%
トピック
- Cell Adhesion Molecules Research5.4%
- Cancer Cells and Metastasis5.2%
- Cellular Mechanics and Interactions3.3%
- Wnt/β-catenin signaling in development and cancer3.1%
- Cancer, Hypoxia, and Metabolism2.2%
- Enzyme function and inhibition2.1%
- その他78.7%
共著者
- Paul C. McDonald36
- Claudiu T. Supuran13
- Shawn C. Chafe13
- Armelle A. Troussard10
- Virginia Gray8
- Calvin D. Roskelley7
- Jasbinder S. Sanghera7
- Marc G. Coppolino7
- Shannon Awrey7
- Yuanmei Lou7
- Chuanyue Wu6
- Daniel J. Renouf6
- Fabrizio Carta6
- Geetha Venkateswaran6
- Gregory E. Hannigan6
- Oksana Nemirovsky6
- René St‐Arnaud6
- Chungyee Leung-Hagesteijn5
- Clara Tan5
- David F. Schaeffer5
- Jean‐Yves Winum5
- Sarah Attwell5
- Wells S. Brown5
- Andrew B. Fielding4
全論文
- Guidelines and definitions for research on epithelial–mesenchymal transition
著者: Jing Yang, Parker B. Antin, Geert Berx, Cédric Blanpain, Thomas Brabletz, Marianne Bronner‐Fraser, Kyra Campbell, Amparo Cano, Jordi Casanova, Gerhard Christofori, Shoukat Dedhar, Rik Derynck, Heide L. Ford, Jonas Fuxe, Antonio García de Herreros, Gregory J. Goodall, Anna‐Katerina Hadjantonakis, Ruby Yun‐Ju Huang, Chaya Kalcheim, Raghu Kalluri, Yibin Kang, Yeesim Khew‐Goodall, Herbert Levine, Jinsong Liu, Gregory D. Longmore, Sendurai A. Mani, Joan Massagué, Roberto Mayor, David R. McClay, Keith E. Mostov, Donald F. Newgreen, M. Ángela Nieto, Alain Puisieux, Raymond B. Runyan, Pierre Savagner, Ben Z. Stanger, Marc P. Stemmler, Yoshiko Takahashi, Masatoshi Takeichi, Eric Théveneau, Jean Paul Thiery, Erik W. Thompson, Robert A. Weinberg, Elizabeth D. Williams, Jianhua Xing, Binhua P. Zhou, Guojun Sheng - Nature Reviews Molecular Cell Biology 2020 被引用: 2,301
- A Phase 1 Study of SLC-0111, a Novel Inhibitor of Carbonic Anhydrase IX, in Patients With Advanced Solid Tumors
著者: Paul C. McDonald, Stephen Chia, Philippe L. Bédard, Quincy Chu, Michael P. A. Lyle, Liren Tang, Madhu Singh, Zaihui Zhang, Claudiu T. Supuran, Daniel J. Renouf, Shoukat Dedhar - American Journal of Clinical Oncology 2020 被引用: 250
- Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia
著者: Paul C. McDonald, Shawn C. Chafe, Wells S. Brown, Saeed Saberi, Mridula Swayampakula, Geetha Venkateswaran, Oksana Nemirovsky, Jordan Gillespie, Joanna M. Karasinska, Steve E. Kalloger, Claudiu T. Supuran, David F. Schaeffer, Ali Bashashati, Sohrab P. Shah, James T. Topham, Donald T. Yapp, Jinyang Li, Daniel J. Renouf, Ben Z. Stanger, Shoukat Dedhar - Gastroenterology 2019 被引用: 232
- Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors
著者: Shawn C. Chafe, Frederick S. Vizeacoumar, Geetha Venkateswaran, Oksana Nemirovsky, Shannon Awrey, Wells S. Brown, Paul C. McDonald, Fabrizio Carta, Andrew Metcalfe, Joanna M. Karasinska, Ling Huang, Senthil K. Muthuswamy, David F. Schaeffer, Daniel J. Renouf, Claudiu T. Supuran, Franco J. Vizeacoumar, Shoukat Dedhar - Science Advances 2021 被引用: 139
- Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors
著者: Yuanmei Lou, Paul C. McDonald, Arusha Oloumi, Stephen Chia, Christina Ostlund, Ardalan Ahmadi, Alastair H. Kyle, Ulrich auf dem Keller, Samuel Leung, David Huntsman, Blaise Clarke, Brent W. Sutherland, Dawn Waterhouse, Marcel B. Bally, Calvin D. Roskelley, Christopher M. Overall, Andrew I. Minchinton, Fabio Pacchiano, Fabrizio Carta, Andrea Scozzafava, Nadia Touisni, Jean‐Yves Winum, Claudiu T. Supuran, Shoukat Dedhar - Cancer Research 2011 被引用: 756
- Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer
著者: Wells S. Brown, Paul C. McDonald, Oksana Nemirovsky, Shannon Awrey, Shawn C. Chafe, David F. Schaeffer, Jinyang Li, Daniel J. Renouf, Ben Z. Stanger, Shoukat Dedhar - Cell Reports Medicine 2020 被引用: 108
- Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis
著者: Fabio Pacchiano, Fabrizio Carta, Paul C. McDonald, Yuanmei Lou, Daniela Vullo, Andrea Scozzafava, Shoukat Dedhar, Claudiu T. Supuran - Journal of Medicinal Chemistry 2011 被引用: 514
- Cancer Therapeutic Targeting of Hypoxia Induced Carbonic Anhydrase IX: From Bench to Bedside
著者: Paul C. McDonald, Shawn C. Chafe, Claudiu T. Supuran, Shoukat Dedhar - Cancers 2022 被引用: 108
- Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment
著者: Andrea Angeli, Fabrizio Carta, Alessio Nocentini, Jean‐Yves Winum, Raivis Žalubovskis, Atilla Akdemir, Valentina Onnis, Wagdy M. Eldehna, Clemente Capasso, Giuseppina De Simone, Simona Maria Monti, Simone Carradori, William A. Donald, Shoukat Dedhar, Claudiu T. Supuran - Metabolites 2020 被引用: 174
- Targeting Hypoxia-Induced Carbonic Anhydrase IX Enhances Immune-Checkpoint Blockade Locally and Systemically
著者: Shawn C. Chafe, Paul C. McDonald, Saeed Saberi, Oksana Nemirovsky, Geetha Venkateswaran, Samantha Burugu, Dongxia Gao, Alberto Delaidelli, Alastair H. Kyle, Jennifer H.E. Baker, Jordan Gillespie, Ali Bashashati, Andrew I. Minchinton, Youwen Zhou, Sohrab P. Shah, Shoukat Dedhar - Cancer Immunology Research 2019 被引用: 161
- The epithelial–mesenchymal transition: new insights in signaling, development, and disease
著者: Jonathan M. Lee, Shoukat Dedhar, Raghu Kalluri, Erik W. Thompson - The Journal of Cell Biology 2006 被引用: 2,032
- β1 integrin, ILK and mTOR regulate collagen synthesis in mechanically loaded tendon cells
著者: Rouhollah Mousavizadeh, Payman Hojabrpour, Felipe Eltit, Paul C. McDonald, Shoukat Dedhar, Robert G. McCormack, Vincent Duronio, Seyed Mehdi Jafarnejad, Alex Scott - Scientific Reports 2020 被引用: 80
- Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche
著者: Frances E. Lock, Paul C. McDonald, Y. Lou, Isabel Serrano, Shawn C. Chafe, Cecilia Östlund, Samuel Aparício, J-Y Winum, Claudiu T. Supuran, Shoukat Dedhar - Oncogene 2012 被引用: 345
- Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase
著者: Isabel Serrano, Paul C. McDonald, Frances E. Lock, William J. Muller, Shoukat Dedhar - Nature Communications 2013 被引用: 223
- Integrin-linked kinase: a cancer therapeutic target unique among its ILK
著者: Gregory E. Hannigan, Armelle A. Troussard, Shoukat Dedhar - Nature reviews. Cancer 2005 被引用: 597
- Recent Developments in Targeting Carbonic Anhydrase IX for Cancer Therapeutics
著者: Paul C. McDonald, Jean‐Yves Winum, Claudiu T. Supuran, Shoukat Dedhar - Oncotarget 2012 被引用: 413
- Overcoming Hypoxia-Mediated Tumor Progression: Combinatorial Approaches Targeting pH Regulation, Angiogenesis and Immune Dysfunction
著者: Paul C. McDonald, Shawn C. Chafe, Shoukat Dedhar - Frontiers in Cell and Developmental Biology 2016 被引用: 147
- A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells
著者: Geetha Venkateswaran, Paul C. McDonald, Shawn C. Chafe, Wells S. Brown, Zachary J. Gerbec, Shannon Awrey, Seth J. Parker, Shoukat Dedhar - Molecular Cancer Therapeutics 2023 被引用: 26
- Reciprocal interactions between β1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: A different perspective in epithelial biology
著者: Fei Wang, Valerie M. Weaver, Ole W. Petersen, Carolyn A. Larabell, Shoukat Dedhar, Per Briand, Ruth Lupu, Mina J. Bissell - National Academy of Sciences, Proceedings of the National Academy of Sciences 1998 被引用: 640
- Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo
著者: Nathaniel Boyd, Kiera Walker, Joshua Fried, James R. Hackney, Paul C. McDonald, Gloria A. Benavides, Raffaella Spina, Alessandra Audia, Sarah Scott, Catherine Libby, Anh Tran, Mark O. Bevensee, Corinne E. Griguer, Susan E. Nozell, G. Yancey Gillespie, Burt Nabors, Krishna Bhat, Eli E. Bar, Victor Darley‐Usmar, Bo Xu, Emily R. Gordon, Sara J. Cooper, Shoukat Dedhar, Anita B. Hjelmeland - JCI Insight 2017 被引用: 120
- Persister cell plasticity in tumour drug resistance
著者: Paul C. McDonald, Shoukat Dedhar - Seminars in Cell and Developmental Biology 2023 被引用: 22
- Regulation of Protein Kinase B/Akt-Serine 473 Phosphorylation by Integrin-linked Kinase
著者: Sujata Persad, Sarah Attwell, Virginia Gray, Nasrin M. Mawji, Jing Deng, Dan Leung, Jun Yan, Jasbinder S. Sanghera, Michael P. Walsh, Shoukat Dedhar - Journal of Biological Chemistry 2001 被引用: 501
- Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells
著者: Brent W. Sutherland, Jill E. Kucab, Joyce C. Wu, Cathy Lee, Maggie C.U. Cheang, Erika Yorida, Dmitry Turbin, Shoukat Dedhar, Colleen C. Nelson, Michaël Pollak, H. Leighton Grimes, Kathy D. Miller, Sunil Badve, David G. Huntsman, C Blake-Gilks, Min Chen, Catherine J. Pallen, Sandra E. Dunn - Oncogene 2005 被引用: 305
- Neuroprotection via matrix-trophic coupling between cerebral endothelial cells and neurons
著者: Shuzhen Guo, Woo Jean Kim, Josephine Lok, Sun-Ryung Lee, Elaine Besancon, Bing‐Hao Luo, Monique F. Stins, Xiaoying Wang, Shoukat Dedhar, Eng H. Lo - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 被引用: 254
