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Simon F. Lacey

1992–2023 年に発表

102
論文数
36,346
被引用数
76
h 指数
102
i10 指数

被引用数

Simon F. Lacey の年別被引用数1991 年: 被引用 3 件1993 年: 被引用 1 件1994 年: 被引用 5 件1995 年: 被引用 6 件1996 年: 被引用 8 件1997 年: 被引用 3 件1998 年: 被引用 5 件1999 年: 被引用 4 件2000 年: 被引用 7 件2001 年: 被引用 4 件2002 年: 被引用 3 件2003 年: 被引用 6 件2004 年: 被引用 6 件2005 年: 被引用 5 件2006 年: 被引用 4 件2007 年: 被引用 4 件2008 年: 被引用 9 件2009 年: 被引用 9 件2010 年: 被引用 10 件2011 年: 被引用 16 件2012 年: 被引用 25 件2013 年: 被引用 16 件2014 年: 被引用 19 件2015 年: 被引用 105 件2016 年: 被引用 295 件2017 年: 被引用 457 件2018 年: 被引用 761 件2019 年: 被引用 2,017 件2020 年: 被引用 2,897 件2021 年: 被引用 3,008 件2022 年: 被引用 2,473 件2023 年: 被引用 2,009 件2024 年: 被引用 2,805 件2025 年: 被引用 1,515 件2026 年: 被引用 47 件1992 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 5,174 件、この内訳の 32.5%中国: 引用元論文 2,293 件、この内訳の 14.4%ドイツ: 引用元論文 1,046 件、この内訳の 6.6%イギリス: 引用元論文 758 件、この内訳の 4.7%イタリア: 引用元論文 601 件、この内訳の 3.8%フランス: 引用元論文 513 件、この内訳の 3.2%カナダ: 引用元論文 432 件、この内訳の 2.7%スペイン: 引用元論文 429 件、この内訳の 2.7%スイス: 引用元論文 392 件、この内訳の 2.5%オーストラリア: 引用元論文 376 件、この内訳の 2.3%オランダ: 引用元論文 335 件、この内訳の 2.1%日本: 引用元論文 298 件、この内訳の 1.9%
0%32.5%その他 20.6%

機関

分野

  • Medicine77.9%
  • Biochemistry, Genetics and Molecular Biology11.1%
  • Immunology and Microbiology8.7%
  • Engineering1%
  • Neuroscience0.5%
  • Materials Science0.3%
  • その他0.5%

トピック

  • CAR-T cell therapy research21.3%
  • Immune Cell Function and Interaction6.5%
  • Virus-based gene therapy research5.9%
  • Immunotherapy and Immune Responses5.4%
  • Cancer Immunotherapy and Biomarkers4%
  • Nanowire Synthesis and Applications3.9%
  • その他53%

共著者

全論文

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  1. Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

    著者: Shannon L. Maude, Noelle V. Frey, Pamela A. Shaw, Richard Aplenc, David M. Barrett, Nancy Bunin, Anne Chew, Vanessa Gonzalez, Zhaohui Zheng, Simon F. Lacey, Yolanda D. Mahnke, J. Joseph Melenhorst, Susan R. Rheingold, Angela Shen, David T. Teachey, Bruce L. Levine, Carl H. June, David L. Porter, Stephan A. Grupp - New England Journal of Medicine 2014 被引用: 5,408

  2. Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

    著者: Joseph A. Fraietta, Simon F. Lacey, Elena J. Orlando, Iulian Pruteanu-Malinici, Mercy Gohil, Stefan Lundh, Alina C. Boesteanu, Yan Wang, Roddy S. O’Connor, Wei‐Ting Hwang, Edward Pequignot, David E Ambrose, Changfeng Zhang, Nicholas S. Wilcox, Felipe Bedoya, Corin L. Dorfmeier, Chen Fang, Lifeng Tian, Harit Parakandi, Minnal Gupta, Regina M. Young, F. Brad Johnson, Irina Kulikovskaya, Li Liu, Jun Xu, Sadik H. Kassim, Megan M. Davis, Bruce L. Levine, Noelle V. Frey, Donald L. Siegel, Alexander C. Huang, E. John Wherry, Hans Bitter, Jennifer L. Brogdon, David L. Porter, Carl H. June, J. Joseph Melenhorst - Nature Medicine 2018 被引用: 1,770

  3. A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma

    著者: Donald M. O’Rourke, MacLean P. Nasrallah, Arati Desai, J. Joseph Melenhorst, Keith G. Mansfield, Jennifer J.D. Morrissette, Maria Martinez‐Lage, Steven Brem, Eileen Maloney, Angela Shen, Randi Isaacs, Suyash Mohan, Gabriela Plesa, Simon F. Lacey, Jean‐Marc Navenot, Zhaohui Zheng, Bruce L. Levine, Hideho Okada, Carl H. June, Jennifer L. Brogdon, Marcela V. Maus - Science Translational Medicine 2017 被引用: 1,772

  4. CRISPR-engineered T cells in patients with refractory cancer

    著者: Edward A. Stadtmauer, Joseph A. Fraietta, Megan M. Davis, Adam D. Cohen, Kristy Weber, Eric Lancaster, Patricia Mangan, Irina Kulikovskaya, Minnal Gupta, Fang Chen, Lifeng Tian, Vanessa Gonzalez, Jun Xu, In-Young Jung, J. Joseph Melenhorst, Gabriela Plesa, Joanne Shea, Tina Matlawski, Amanda Cervini, Avery L. Gaymon, Stephanie Desjardins, Anne Lamontagne, January Salas-McKee, Andrew D. Fesnak, Donald L. Siegel, Bruce L. Levine, Julie K. Jadlowsky, Regina M. Young, Anne Chew, Wei‐Ting Hwang, Elizabeth O. Hexner, Beatriz M. Carreno, Christopher L. Nobles, Frederic D. Bushman, Kevin R. Parker, Yanyan Qi, Ansuman T. Satpathy, Howard Y. Chang, Yangbing Zhao, Simon F. Lacey, Carl H. June - Science 2020 被引用: 1,484

  5. Decade-long leukaemia remissions with persistence of CD4+ CAR T cells

    著者: J. Joseph Melenhorst, Gregory M. Chen, Meng Wang, David L. Porter, Changya Chen, McKensie Collins, Peng Gao, Shovik Bandyopadhyay, Hongxing Sun, Ziran Zhao, Stefan Lundh, Iulian Pruteanu-Malinici, Christopher L. Nobles, Sayantan Maji, Noelle V. Frey, Saar Gill, Alison W. Loren, Lifeng Tian, Irina Kulikovskaya, Minnal Gupta, David E Ambrose, Megan M. Davis, Joseph A. Fraietta, Jennifer L. Brogdon, Regina M. Young, Anne Chew, Bruce L. Levine, Donald L. Siegel, Cécile Alanio, E. John Wherry, Frederic D. Bushman, Simon F. Lacey, Kai Tan, Carl H. June - Nature 2022 被引用: 947

  6. Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas

    著者: Stephen J. Schuster, Jakub Svoboda, Elise A. Chong, Sunita D. Nasta, Anthony R. Mato, Özlem Anak, Jennifer L. Brogdon, Iulian Pruteanu-Malinici, Vijay Bhoj, Daniel J. Landsburg, Mariusz A. Wasik, Bruce L. Levine, Simon F. Lacey, J. Joseph Melenhorst, David L. Porter, Carl H. June - New England Journal of Medicine 2017 被引用: 1,854

  7. Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

    著者: Joseph A. Fraietta, Christopher L. Nobles, Morgan A. Sammons, Stefan Lundh, Shannon A. Carty, Tyler J. Reich, Alexandria P. Cogdill, Jennifer J.D. Morrissette, Jamie E. DeNizio, Shantan Reddy, Young Sun Hwang, Mercy Gohil, Irina Kulikovskaya, Farzana Nazimuddin, Minnal Gupta, Fang Chen, J.K. Everett, Katherine A. Alexander, Enrique Lin-Shiao, Marvin H. Gee, Xiaojun Liu, Regina M. Young, David E Ambrose, Yan Wang, Jun Xu, Martha S. Jordan, Katherine T. Marcucci, Bruce L. Levine, K. Christopher García, Yangbing Zhao, Michael Kalos, David Porter, Rahul M. Kohli, Simon F. Lacey, Shelley L. Berger, Frederic D. Bushman, Carl H. June, J. Joseph Melenhorst - Nature 2018 被引用: 873

  8. PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial

    著者: Vivek Narayan, Julie S. Barber-Rotenberg, In-Young Jung, Simon F. Lacey, Andrew J. Rech, Megan M. Davis, Wei‐Ting Hwang, Priti Lal, Erica L. Carpenter, Shannon L. Maude, Gabriela Plesa, Neha Vapiwala, Anne Chew, Michael Moniak, Ronnie Sebro, Michael D. Farwell, Amy Marshall, Joan Gilmore, Lester Lledo, Karen Dengel, S. Church, Tyler Hether, Jun Xu, Mercy Gohil, Thomas H. Buckingham, Stephanie S. Yee, Vanessa Gonzalez, Irina Kulikovskaya, Fang Chen, Lifeng Tian, Kyle Tien, Whitney L. Gladney, Christopher L. Nobles, Hayley E. Raymond, Prostate Cancer Cellular Therapy Program Investigators, Diane Frazee, Mary Truran, Elizabeth Veloso, Holly McConville, Jonathan Aguedelo, Samantha Hower, Sophia Ngo, Julie K. Jadlowsky, J. Joseph Melenhorst, Aoife M. Roche, J.K. Everett, Minnal Gupta, Farzana Nazimuddin, Chelsie Bartoszek, Natalka Koterba, Rachael Reynolds, Farris Ellington, Christopher C. Kloss, Ji‐Hyun Lee, Yangbing Zhao, John Scholler, James L. Riley, Christina Bailey, Andrew J. P. White, Briana M. Hudson, Pearl Chang, Marcela V. Maus, Bruce L. Levine, Elizabeth O. Hexner, Donald L. Siegel, Frederic D. Bushman, Carl H. June, Joseph A. Fraietta, Naomi B. Haas - Nature Medicine 2022 被引用: 500

  9. Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia

    著者: David Porter, Wei‐Ting Hwang, Noelle V. Frey, Simon F. Lacey, Pamela A. Shaw, Alison W. Loren, Adam Bagg, Katherine T. Marcucci, Angela Shen, Vanessa Gonzalez, David E Ambrose, Stephan A. Grupp, Anne Chew, Zhaohui Zheng, Michael C. Milone, Bruce L. Levine, J. Joseph Melenhorst, Carl H. June - Science Translational Medicine 2015 被引用: 1,727

  10. An NK-like CAR T cell transition in CAR T cell dysfunction

    著者: Charly R. Good, M. Ángela Aznar, Shunichiro Kuramitsu, Parisa Samareh, Sangya Agarwal, Greg Donahue, Kenichi Ishiyama, Nils Wellhausen, Austin K. Rennels, Yujie Ma, Lifeng Tian, Sònia Guedan, Katherine A. Alexander, Zhen Zhang, Philipp C. Rommel, Nathan Singh, Karl M. Glastad, Max W. Richardson, Keisuke Watanabe, János L. Tanyi, Mark H. O’Hara, Marco Ruella, Simon F. Lacey, Edmund K. Moon, Stephen J. Schuster, Steven Μ. Albelda, Lewis L. Lanier, Regina M. Young, Shelley L. Berger, Carl H. June - Cell 2021 被引用: 417

  11. Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy

    著者: Elena Sotillo, David M. Barrett, Kathryn L. Black, Asen Bagashev, Derek A. Oldridge, Glendon Wu, Robyn T. Sussman, Claudia Lanauze, Marco Ruella, Matthew R. Gazzara, Nicole M. Martínez, Colleen T. Harrington, Elaine Y. Chung, Jessica Perazzelli, Ted J. Hofmann, Shannon L. Maude, Pichai Raman, Alejandro Barrera, Saar Gill, Simon F. Lacey, Jan J. Melenhorst, David Allman, Elad Jacoby, Terry J. Fry, Crystal L. Mackall, Yoseph Barash, Kristen W. Lynch, John M. Maris, Stephan A. Grupp, Andrei Thomas‐Tikhonenko - Cancer Discovery 2015 被引用: 1,254

  12. Dominant-Negative TGF-β Receptor Enhances PSMA-Targeted Human CAR T Cell Proliferation And Augments Prostate Cancer Eradication

    著者: Christopher C. Kloss, Ji‐Hyun Lee, Aaron Zhang, Fang Chen, J. Joseph Melenhorst, Simon F. Lacey, Marcela V. Maus, Joseph A. Fraietta, Yangbing Zhao, Carl H. June - Molecular Therapy 2018 被引用: 623

  13. B cell maturation antigen–specific CAR T cells are clinically active in multiple myeloma

    著者: Adam D. Cohen, Alfred L. Garfall, Edward A. Stadtmauer, J. Joseph Melenhorst, Simon F. Lacey, Eric Lancaster, Dan T. Vogl, Brendan M. Weiss, Karen Dengel, Annemarie Nelson, Gabriela Plesa, Fang Chen, Megan M. Davis, Wei‐Ting Hwang, Regina M. Young, Jennifer L. Brogdon, Randi Isaacs, Iulian Pruteanu-Malinici, Don L. Siegel, Bruce L. Levine, Carl H. June, Michael C. Milone - Journal of Clinical Investigation 2019 被引用: 790

  14. Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia

    著者: David T. Teachey, Simon F. Lacey, Pamela A. Shaw, J. Joseph Melenhorst, Shannon L. Maude, Noelle V. Frey, Edward Pequignot, Vanessa Gonzalez, Fang Chen, Jeffrey Finklestein, David M. Barrett, Scott L. Weiss, Julie C. Fitzgerald, Robert A. Berg, Richard Aplenc, Colleen Callahan, Susan R. Rheingold, Zhaohui Zheng, Stefan Rose‐John, Jason C. White, Farzana Nazimuddin, Gerald Wertheim, Bruce L. Levine, Carl H. June, David L. Porter, Stephan A. Grupp - Cancer Discovery 2016 被引用: 1,084

  15. Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell

    著者: Marco Ruella, Jun Xu, David M. Barrett, Joseph A. Fraietta, Tyler J. Reich, David E Ambrose, Michael Klichinsky, Olga Shestova, Prachi Patel, Irina Kulikovskaya, Farzana Nazimuddin, Vijay Bhoj, Elena J. Orlando, Terry J. Fry, Hans Bitter, Shannon L. Maude, Bruce L. Levine, Christopher L. Nobles, Frederic D. Bushman, Regina M. Young, John Scholler, Saar Gill, Carl H. June, Stephan A. Grupp, Simon F. Lacey, J. Joseph Melenhorst - Nature Medicine 2018 被引用: 645

  16. Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation

    著者: Sònia Guedan, Avery D. Posey, Carolyn E. Shaw, Anna Wing, Tong Da, Prachi Patel, Shannon E. McGettigan, Victoria Casado‐Medrano, Omkar U. Kawalekar, Mireia Uribe‐Herranz, Decheng Song, J. Joseph Melenhorst, Simon F. Lacey, John Scholler, Brian Keith, Regina M. Young, Carl H. June - JCI Insight 2018 被引用: 580

  17. Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer

    著者: Julia Tchou, Yangbing Zhao, Bruce L. Levine, Paul J. Zhang, Megan M. Davis, J. Joseph Melenhorst, Irina Kulikovskaya, Andrea Brennan, Xiaojun Liu, Simon F. Lacey, Avery D. Posey, Austin D. Williams, Alycia So, José R. Conejo-García, Gabriela Plesa, Regina M. Young, Shannon E. McGettigan, Jean S. Campbell, Robert H. Pierce, Jennifer M. Matro, Angela DeMichele, Amy S. Clark, Laurence J.N. Cooper, Lynn M. Schuchter, Robert H. Vonderheide, Carl H. June - Cancer Immunology Research 2017 被引用: 443

  18. Activity of Mesothelin-Specific Chimeric Antigen Receptor T Cells Against Pancreatic Carcinoma Metastases in a Phase 1 Trial

    著者: Gregory L. Beatty, Mark H. O’Hara, Simon F. Lacey, Drew A. Torigian, Farzana Nazimuddin, Fang Chen, Irina Kulikovskaya, Michael C. Soulen, Maureen McGarvey, Anne Marie Nelson, Whitney L. Gladney, Bruce L. Levine, J. Joseph Melenhorst, Gabriela Plesa, Carl H. June - Gastroenterology 2018 被引用: 500

  19. Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

    著者: Divij Mathew, Josephine R. Giles, Amy E. Baxter, Derek A. Oldridge, Allison R. Greenplate, Jennifer E. Wu, Cécile Alanio, Leticia Kuri-Cervantes, M. Betina Pampena, Kurt D’Andrea, Sasikanth Manne, Zeyu Chen, Yinghui Huang, John P. Reilly, Ariel R. Weisman, C.A.G. Ittner, Oliva Kuthuru, Jeanette Dougherty, Kito Nzingha, Nicholas Han, Justin Kim, Ajinkya Pattekar, Eileen C. Goodwin, Elizabeth M. Anderson, Madison E. Weirick, Sigrid Gouma, Claudia P. Arevalo, Marcus J. Bolton, Chen Fang, Simon F. Lacey, Holly Ramage, Sara Cherry, Scott E. Hensley, Sokratis A. Apostolidis, Alexander C. Huang, Laura A. Vella, The UPenn COVID Processing Unit, Michael R. Betts, Nuala J. Meyer, E. John Wherry, Zahidul Alam, Mary M. Addison, Katelyn T. Byrne, Aditi Chandra, Hélène C. Descamps, Yaroslav Kaminskiy, Jacob T. Hamilton, Julia Han Noll, Dalia K. Omran, Eric Perkey, Elizabeth M. Prager, Dana Pueschl, Jennifer Shah, Jake Shilan, Ashley Vanderbeck - Science 2020 被引用: 1,662

  20. Phase I Study of Lentiviral-Transduced Chimeric Antigen Receptor-Modified T Cells Recognizing Mesothelin in Advanced Solid Cancers

    著者: Andrew R. Haas, János L. Tanyi, Mark H. O’Hara, Whitney L. Gladney, Simon F. Lacey, Drew A. Torigian, Michael C. Soulen, Lifeng Tian, Maureen McGarvey, Anne Marie Nelson, Caitlin S. Farabaugh, Edmund K. Moon, Bruce L. Levine, J. Joseph Melenhorst, Gabriela Plesa, Carl H. June, Steven Μ. Albelda, Gregory L. Beatty - Molecular Therapy 2019 被引用: 371

  21. Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells

    著者: Saba Ghassemi, Selene Nuñez-Cruz, Roddy S. O’Connor, Joseph A. Fraietta, Prachi Patel, John Scholler, David M. Barrett, Stefan Lundh, Megan M. Davis, Felipe Bedoya, Changfeng Zhang, John Leferovich, Simon F. Lacey, Bruce L. Levine, Stephan A. Grupp, Carl H. June, J. Joseph Melenhorst, Michael C. Milone - Cancer Immunology Research 2018 被引用: 302

  22. NY-ESO-1–specific TCR–engineered T cells mediate sustained antigen-specific antitumor effects in myeloma

    著者: Aaron P. Rapoport, Edward A. Stadtmauer, Gwendolyn Binder-Scholl, Olga Goloubeva, Dan T. Vogl, Simon F. Lacey, Ashraf Badros, Alfred L. Garfall, Brendan M. Weiss, Jeffrey Finklestein, Irina Kulikovskaya, Sanjoy K. Sinha, Shari S. Kronsberg, Minnal Gupta, Sarah Bond, Luca Melchiori, Joanna E. Brewer, Alan Bennett, Andrew B. Gerry, Nicholas J. Pumphrey, Daniel Williams, Helen K Tayton- Martin, Lilliam Ribeiro, Tom Holdich, Saul Yanovich, Nancy M. Hardy, Jean A. Yared, Naseem Kerr, Sunita Philip, Sandra Westphal, Don L. Siegel, Bruce L. Levine, Bent K. Jakobsen, Michael Kalos, Carl H. June - Nature Medicine 2015 被引用: 848

  23. BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T cell stemness and exhaustion

    著者: In-Young Jung, Vivek Narayan, Sierra J. McDonald, Andrew J. Rech, Robert L. Bartoszek, Gwanui Hong, Megan M. Davis, Jun Xu, Alina C. Boesteanu, Julie S. Barber-Rotenberg, Gabriela Plesa, Simon F. Lacey, Julie K. Jadlowsky, Donald L. Siegel, Dana M. Hammill, Park F. Cho-Park, Shelley L. Berger, Naomi B. Haas, Joseph A. Fraietta - Science Translational Medicine 2022 被引用: 129

  24. Pembrolizumab for B-cell lymphomas relapsing after or refractory to CD19-directed CAR T-cell therapy

    著者: Elise A. Chong, Cécile Alanio, Jakub Svoboda, Sunita D. Nasta, Daniel J. Landsburg, Simon F. Lacey, Marco Ruella, Siddharth Bhattacharyya, E. John Wherry, Stephen J. Schuster - Blood 2021 被引用: 191