Stephen Neidle
1972–2025 年に発表
- 149
- 論文数
- 31,059
- 被引用数
- 101
- h 指数
- 144
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology73.8%
- Medicine12.5%
- Chemistry4.3%
- Computer Science2.2%
- Materials Science1.5%
- Pharmacology, Toxicology and Pharmaceutics1.3%
- その他4.4%
トピック
- DNA and Nucleic Acid Chemistry20.1%
- Advanced biosensing and bioanalysis techniques16.3%
- RNA Interference and Gene Delivery10.1%
- RNA and protein synthesis mechanisms6.7%
- Metal complexes synthesis and properties2%
- Bacteriophages and microbial interactions1.7%
- その他43.1%
共著者
- Gary N. Parkinson26
- Anthony P. Reszka19
- Shozeb Haider18
- W. David Wilson18
- Mekala Gunaratnam15
- Lloyd R. Kèlland11
- Martin A. Read9
- Sharon Gowan9
- Terence C. Jenkins9
- David W. Boykin7
- Helen M. Berman7
- Shankar Balasubramanian7
- Stephan A. Ohnmacht7
- Alan K. Todd6
- Christoph Schultes6
- Farial A. Tanious6
- Jane V. Skelly6
- Ahmed A. Ahmed5
- Charles A. Laughton5
- David E. Thurston5
- Gavin W. Collie5
- Laurence H. Hurley5
- R. John Harrison5
- Ramón Vilar5
全論文
- Quadruplex DNA: sequence, topology and structure
著者: Sarah Burge, Gary N. Parkinson, Pascale Hazel, Alan K. Todd, Stephen Neidle - Nucleic Acids Research 2006 被引用: 2,394
- Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
著者: Shankar Balasubramanian, Laurence H. Hurley, Stephen Neidle - Nature Reviews Drug Discovery 2011 被引用: 1,699
- Crystal structure of parallel quadruplexes from human telomeric DNA
著者: Gary N. Parkinson, Michael P. H. Lee, Stephen Neidle - Nature 2002 被引用: 2,038
- Quadruplex nucleic acids as targets for anticancer therapeutics
著者: Stephen Neidle - Nature Reviews Chemistry 2017 被引用: 459
- Quadruplex Nucleic Acids as Novel Therapeutic Targets
著者: Stephen Neidle - Journal of Medicinal Chemistry 2016 被引用: 584
- The G-Quadruplex-Interactive Molecule BRACO-19 Inhibits Tumor Growth, Consistent with Telomere Targeting and Interference with Telomerase Function
著者: Angelika M. Burger, Fangping Dai, Christoph Schultes, Anthony P. Reszka, Michael J. Moore, John A. Double, Stephen Neidle - Cancer Research 2005 被引用: 566
- Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule
著者: Chiara Marchetti, Katherine G. Zyner, Stephan A. Ohnmacht, Mathew Robson, Shozeb Haider, Jennifer P. Morton, Giovanni Marsico, Tam Vo, Sarah Laughlin, Ahmed A. Ahmed, Gloria Di Vita, Ingrida Pazitna, Mekala Gunaratnam, Rachael J. Besser, Ana Clara Andrade, Seckou Diocou, Jeremy A. Pike, David Tannahill, R. Barbara Pedley, T.R. Jeffry Evans, W. David Wilson, Shankar Balasubramanian, Stephen Neidle - Journal of Medicinal Chemistry 2018 被引用: 157
- Inhibition of Human Telomerase by a G-Quadruplex-Interactive Compound
著者: Daekyu Sun, Brian Thompson, Brian E. Cathers, Miguel Salazar, Sean M. Kerwin, John O. Trent, Terence C. Jenkins, Stephen Neidle, Laurence H. Hurley - Journal of Medicinal Chemistry 1997 被引用: 784
- Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter
著者: Anh Tuân Phan, Vitaly Kuryavyi, Sarah Burge, Stephen Neidle, Dinshaw J. Patel - Journal of the American Chemical Society 2007 被引用: 455
- Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors
著者: Martin L. Read, R. John Harrison, Bárbara Romagnoli, Farial A. Tanious, Sharon H. Gowan, Anthony P. Reszka, W. David Wilson, Lloyd R. Kèlland, Stephen Neidle - National Academy of Sciences, Proceedings of the National Academy of Sciences 2001 被引用: 484
- G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo
著者: Roberto Simone, Rubika Balendra, Thomas G. Moens, Elisavet Preza, Katherine Wilson, Amanda Heslegrave, Nathaniel S. Woodling, Teresa Niccoli, Javier Gilbert‐Jaramillo, Samir Abdelkarim, Emma L. Clayton, Mica T. M. Clarke, Marie‐Therese Konrad, Andrew J. Nicoll, Jamie S. Mitchell, Andrea Calvo, Adriano Chiò, Henry Houlden, James M. Polke, Mohamed A. Ismail, Chad E. Stephens, Tam Vo, Abdelbasset A. Farahat, W. David Wilson, David W. Boykin, Henrik Zetterberg, Linda Partridge, Selina Wray, Gary N. Parkinson, Stephen Neidle, Rickie Patani, Pietro Fratta, Adrian M. Isaacs - EMBO Molecular Medicine 2017 被引用: 222
- Loop-Length-Dependent Folding of G-Quadruplexes
著者: Pascale Hazel, J Huppert, Shankar Balasubramanian, Stephen Neidle - Journal of the American Chemical Society 2004 被引用: 483
- Asymmetrically Substituted Quadruplex-Binding Naphthalene Diimide Showing Potent Activity in Pancreatic Cancer Models
著者: Ahmed A. Ahmed, Richard Angell, Sally Oxenford, Jenny Worthington, Nicole Williams, Naomi Barton, Thomas G. Fowler, Daniel E. O’Flynn, Mihiro Sunose, Matthew McConville, Tam Vo, W. David Wilson, Saadia A. Karim, Jennifer P. Morton, Stephen Neidle - ACS Medicinal Chemistry Letters 2020 被引用: 57
- Structure–activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling
著者: Ahmed A. Ahmed, Shuang Chen, Maria Roman-Escorza, Richard Angell, Sally Oxenford, Matthew McConville, Naomi Barton, Mihiro Sunose, Dan M. Neidle, Shozeb Haider, Tariq Arshad, Stephen Neidle - Scientific Reports 2024 被引用: 27
- Human telomeric G‐quadruplex: The current status of telomeric G‐quadruplexes as therapeutic targets in human cancer
著者: Stephen Neidle - FEBS Journal 2009 被引用: 542
- G-quadruplex nucleic acids as therapeutic targets
著者: Shankar Balasubramanian, Stephen Neidle - Current Opinion in Chemical Biology 2009 被引用: 581
- Structure-Based Design and Evaluation of Naphthalene Diimide G-Quadruplex Ligands As Telomere Targeting Agents in Pancreatic Cancer Cells
著者: Marialuisa Micco, Gavin W. Collie, Aaron G. Dale, Stephan A. Ohnmacht, Ingrida Pazitna, Mekala Gunaratnam, Anthony P. Reszka, Stephen Neidle - Journal of Medicinal Chemistry 2013 被引用: 183
- Stabilization of G-Quadruplex DNA and Inhibition of Telomerase Activity by Square-Planar Nickel(II) Complexes
著者: Julie Reed, Anna Arola‐Arnal, Stephen Neidle, Ramón Vilar - Journal of the American Chemical Society 2006 被引用: 333
- A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer
著者: Stephan A. Ohnmacht, Chiara Marchetti, Mekala Gunaratnam, Rachael J. Besser, Shozeb Haider, Gloria Di Vita, Helen L. Lowe, Maria Mellinas‐Gomez, Seckou Diocou, Mathew Robson, Jiřı́ Šponer, Barira Islam, RB Pedley, John A. Hartley, Stephen Neidle - Scientific Reports 2015 被引用: 115
- A standard reference frame for the description of nucleic acid base-pair geometry
著者: Wilma K. Olson, Manju Bansal, S.K. Burley, Richard E. Dickerson, Mark Gerstein, Stephen C. Harvey, Udo Heinemann, Xiang‐Jun Lu, Stephen Neidle, Zippora Shakked, Heinz Sklenar, Masashi Suzuki, Chang‐Shung Tung, Éric Westhof, Cynthia Wolberger, Helen M. Berman - Journal of Molecular Biology 2001 被引用: 602
- Putative DNA Quadruplex Formation within the Human c-kit Oncogene
著者: Sarah Rankin, Anthony P. Reszka, J Huppert, Mire Zloh, Gary N. Parkinson, Alan K. Todd, Sylvain Ladame, Shankar Balasubramanian, Stephen Neidle - Journal of the American Chemical Society 2005 被引用: 549
- Structural Basis of DNA Quadruplex Recognition by an Acridine Drug
著者: N. Campbell, Gary N. Parkinson, Anthony P. Reszka, Stephen Neidle - Journal of the American Chemical Society 2008 被引用: 315
- A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex
著者: Gavin W. Collie, Shozeb Haider, Stephen Neidle, Gary N. Parkinson - Nucleic Acids Research 2010 被引用: 251
- Molecular Dynamics and Principal Components Analysis of Human Telomeric Quadruplex Multimers
著者: Shozeb Haider, Gary N. Parkinson, Stephen Neidle - Biophysical Journal 2008 被引用: 213
