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Tomáš Cihlář

1992–2025 年に発表

93
論文数
20,453
被引用数
63
h 指数
88
i10 指数

被引用数

Tomáš Cihlář の年別被引用数1993 年: 被引用 2 件1994 年: 被引用 1 件1996 年: 被引用 1 件1997 年: 被引用 4 件1998 年: 被引用 3 件1999 年: 被引用 9 件2000 年: 被引用 12 件2001 年: 被引用 25 件2002 年: 被引用 47 件2003 年: 被引用 63 件2004 年: 被引用 62 件2005 年: 被引用 60 件2006 年: 被引用 46 件2007 年: 被引用 39 件2008 年: 被引用 57 件2009 年: 被引用 74 件2010 年: 被引用 68 件2011 年: 被引用 62 件2012 年: 被引用 47 件2013 年: 被引用 54 件2014 年: 被引用 67 件2015 年: 被引用 88 件2016 年: 被引用 65 件2017 年: 被引用 87 件2018 年: 被引用 111 件2019 年: 被引用 341 件2020 年: 被引用 2,904 件2021 年: 被引用 1,617 件2022 年: 被引用 744 件2023 年: 被引用 389 件2024 年: 被引用 564 件2025 年: 被引用 273 件2026 年: 被引用 8 件1995 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 1,987 件、この内訳の 27%中国: 引用元論文 628 件、この内訳の 8.5%インド: 引用元論文 411 件、この内訳の 5.6%イギリス: 引用元論文 368 件、この内訳の 5%ドイツ: 引用元論文 274 件、この内訳の 3.7%イタリア: 引用元論文 258 件、この内訳の 3.5%フランス: 引用元論文 256 件、この内訳の 3.5%カナダ: 引用元論文 218 件、この内訳の 3%スペイン: 引用元論文 187 件、この内訳の 2.5%ベルギー: 引用元論文 185 件、この内訳の 2.5%日本: 引用元論文 174 件、この内訳の 2.4%オーストラリア: 引用元論文 144 件、この内訳の 2%
0%27%その他 30.8%

機関

分野

  • Medicine71.1%
  • Immunology and Microbiology11.4%
  • Biochemistry, Genetics and Molecular Biology6.4%
  • Computer Science4.2%
  • Pharmacology, Toxicology and Pharmaceutics1.8%
  • Chemistry1.2%
  • その他3.9%

トピック

  • SARS-CoV-2 and COVID-19 Research13.3%
  • COVID-19 Clinical Research Studies10.9%
  • HIV/AIDS drug development and treatment6.3%
  • HIV Research and Treatment6.2%
  • Long-Term Effects of COVID-193.2%
  • Computational Drug Discovery Methods3.2%
  • その他56.9%

共著者

全論文

検索で開く
  1. Clinical targeting of HIV capsid protein with a long-acting small molecule

    著者: John O. Link, Martin S. Rhee, Winston C. Tse, Jim Zheng, John R. Somoza, William Rowe, Rebecca Begley, Anna Chiu, Andrew Mulato, Derek Hansen, Eric A. Singer, Luong Tsai, Rujuta A. Bam, Chien‐Hung Chou, Eda Canales, Gediminas Brizgys, Jennifer R. Zhang, Jiayao Li, Michael Graupe, Philip Morganelli, Qi Liu, Qiaoyin Wu, Randall L. Halcomb, Roland D. Saito, Scott D. Schroeder, Scott E. Lazerwith, Steven Bondy, Debi Jin, Magdeleine Hung, Nikolai Novikov, Xiaohong Liu, Armando G. Villaseñor, Carina Cannizzaro, Eric Hu, Robert L. Anderson, T.C. Appleby, Bing Lu, Judy Mwangi, Albert Liclican, Anita Niedziela‐Majka, Giuseppe A. Papalia, Melanie Wong, Stephanie A. Leavitt, Yili Xu, David Koditek, George Stepan, Helen Yu, Nikos Pagratis, Sheila Clancy, Shekeba Ahmadyar, Terrence Z. Cai, Scott Sellers, Scott A. Wolckenhauer, John Ling, Christian Callebaut, Nicolas Margot, Renee R. Ram, Ya-Pei Liu, Rob H. Hyland, Gary Sinclair, Peter Ruane, Gordon Crofoot, Cheryl McDonald, Diana M. Brainard, Latesh Lad, S. Swaminathan, Wesley I. Sundquist, Roman Sakowicz, Anne Chester, William Lee, Eric S. Daar, Stephen R. Yant, Tomáš Cihlář - Nature 2020 被引用: 421

  2. Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

    著者: Travis K. Warren, Robert Jordan, Michael K. Lo, Adrian S. Ray, Richard L. Mackman, Veronica Soloveva, Dustin S. Siegel, Michel Perron, Roy Bannister, Hon C. Hui, Nate Larson, Robert G. Strickley, Jay Wells, Kelly S. Stuthman, Sean A. Van Tongeren, Nicole L. Garza, Ginger Donnelly, Amy C. Shurtleff, Cary Retterer, Dima Gharaibeh, Rouzbeh Zamani, Tara Kenny, Brett Eaton, Elizabeth Grimes, Lisa S. Welch, Laura Gomba, Catherine L. Wilhelmsen, Donald K. Nichols, Jonathan E. Nuss, Elyse R. Nagle, Jeffrey R. Kugelman, Gustavo Palacios, Edward Doerffler, Sean Neville, Ernest Carra, Michael O. Clarke, Lijun Zhang, Willard Lew, Bruce S. Ross, Queenie Wang, Kwon Soo Chun, Lydia Wolfe, Darius Babusis, Yeojin Park, Kirsten M. Stray, Iva Trancheva, Joy Y. Feng, Ona Barauskas, Yili Xu, Pamela Wong, Molly R. Braun, Mike Flint, Laura K. McMullan, Shan-Shan Chen, Rachel Fearns, S. Swaminathan, Douglas L. Mayers, Christina F. Spiropoulou, William A. Lee, Stuart T. Nichol, Tomáš Cihlář, Sina Bavari - Nature 2016 被引用: 1,614

  3. Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms

    著者: Laura J. Stevens, Andrea J. Pruijssers, Hery W. Lee, Calvin J. Gordon, Egor P. Tchesnokov, Jennifer Gribble, Amelia S. George, Tia M. Hughes, Xiaotao Lu, Jiani Li, Jason K. Perry, Danielle Porter, Tomáš Cihlář, Timothy P. Sheahan, Ralph S. Baric, Matthias Götte, Mark R. Denison - Science Translational Medicine 2022 被引用: 252

  4. Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

    著者: Timothy P. Sheahan, Amy Sims, Rachel L. Graham, Vineet D. Menachery, Lisa E. Gralinski, James Brett Case, Sarah R. Leist, Krzysztof Pyrć, Joy Y. Feng, Iva Trantcheva, Roy Bannister, Yeojin Park, Darius Babusis, Michael O. Clarke, Richard L. Mackman, Jamie E. Spahn, Christopher A. Palmiotti, Dustin S. Siegel, Adrian S. Ray, Tomáš Cihlář, Robert Jordan, Mark R. Denison, Ralph S. Baric - Science Translational Medicine 2017 被引用: 1,634

  5. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

    著者: Maria L. Agostini, Erica L. Andres, Amy Sims, Rachel L. Graham, Timothy P. Sheahan, Xiaotao Lu, Everett Clinton Smith, James Brett Case, Joy Y. Feng, Robert Jordan, Adrian S. Ray, Tomáš Cihlář, Dustin S. Siegel, Richard L. Mackman, Michael O. Clarke, Ralph S. Baric, Mark R. Denison - mBio 2018 被引用: 1,514

  6. Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys

    著者: Richard L. Mackman, Rao Kalla, Darius Babusis, Jared Pitts, Kimberly T. Barrett, Kwon Soo Chun, Venice Du Pont, Lauren Rodriguez, Jasmine Moshiri, Yili Xu, Michael Lee, Gary Lee, Blake J. Bleier, Anh-Quan Nguyen, B. Michael O’Keefe, Andrea Ambrosi, Meredith Cook, Joy Yu, Kassibla Elodie Dempah, Elaine Bunyan, Nicholas C. Riola, Xianghan Lu, Renmeng Liu, Ashley Davie, Tien-Ying Hsiang, Justin Dearing, Meghan S. Vermillion, Michael Gale, Anita Niedziela‐Majka, Joy Y. Feng, Charlotte Hedskog, John P. Bilello, Raju Subramanian, Tomáš Cihlář - Journal of Medicinal Chemistry 2023 被引用: 63

  7. A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model

    著者: Stephen R. Yant, Andrew Mulato, Derek Hansen, Winston C. Tse, Anita Niedziela‐Majka, Jennifer R. Zhang, George Stepan, Debi Jin, Melanie Wong, Jill M. Perreira, Eric A. Singer, Giuseppe A. Papalia, Eric Hu, Jim Zheng, Bing Lu, Scott D. Schroeder, Kevin Chou, Shekeba Ahmadyar, Albert Liclican, Helen Yu, Nikolai Novikov, Eric E. Paoli, Daniel Gonik, Renee R. Ram, Magdeleine Hung, William M. McDougall, Abraham L. Brass, Wesley I. Sundquist, Tomáš Cihlář, John O. Link - Nature Medicine 2019 被引用: 166

  8. Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice

    著者: Andrea J. Pruijssers, Amelia S. George, Alexandra Schäfer, Sarah R. Leist, Lisa E. Gralinksi, Kenneth H. Dinnon, Boyd L. Yount, Maria L. Agostini, Laura J. Stevens, James D. Chappell, Xiaotao Lu, Tia M. Hughes, Kendra L. Gully, David R. Martinez, Ariane J. Brown, Rachel L. Graham, Jason K. Perry, Venice Du Pont, Jared Pitts, Bin Ma, Darius Babusis, Eisuke Murakami, Joy Y. Feng, John P. Bilello, Danielle Porter, Tomáš Cihlář, Ralph S. Baric, Mark R. Denison, Timothy P. Sheahan - Cell Reports 2020 被引用: 540

  9. Remdesivir (GS-5734) protects African green monkeys from Nipah virus challenge

    著者: Michael K. Lo, Friederike Feldmann, Joy Gary, Robert Jordan, Roy Bannister, Jacqueline Cronin, Nishi Patel, John D. Klena, Stuart T. Nichol, Tomáš Cihlář, Sherif R. Zaki, Heinz Feldmann, Christina F. Spiropoulou, Emmie de Wit - Science Translational Medicine 2019 被引用: 275

  10. GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses

    著者: Michael K. Lo, Robert Jordan, Aaron Arvey, Jawahar Sudhamsu, Punya Shrivastava-Ranjan, Anne L. Hotard, Mike Flint, Laura K. McMullan, Dustin S. Siegel, Michael O. Clarke, Richard L. Mackman, Hon C. Hui, Michel Perron, Adrian S. Ray, Tomáš Cihlář, Stuart T. Nichol, Christina F. Spiropoulou - Scientific Reports 2017 被引用: 515

  11. Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV

    著者: Timothy P. Sheahan, Amy Sims, Sarah R. Leist, Alexandra Schäfer, John J. Won, Ariane J. Brown, Stephanie A. Montgomery, Alison Hogg, Darius Babusis, Michael O. Clarke, Jamie E. Spahn, Laura Bauer, Scott Sellers, Danielle Porter, Joy Y. Feng, Tomáš Cihlář, Robert Jordan, Mark R. Denison, Ralph S. Baric - Nature Communications 2020 被引用: 1,810

  12. Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses

    著者: Dustin S. Siegel, Hon C. Hui, Edward Doerffler, Michael O. Clarke, Kwon Soo Chun, Lijun Zhang, Sean Neville, Ernest Carra, Willard Lew, Bruce S. Ross, Queenie Wang, Lydia Wolfe, Robert Jordan, Veronica Soloveva, John R. Knox, Jason K. Perry, Michel Perron, Kirsten M. Stray, Ona Barauskas, Joy Y. Feng, Yili Xu, Gary Lee, Arnold L. Rheingold, Adrian S. Ray, Roy Bannister, Robert G. Strickley, S. Swaminathan, William A. Lee, Sina Bavari, Tomáš Cihlář, Michael K. Lo, Travis K. Warren, Richard L. Mackman - Journal of Medicinal Chemistry 2017 被引用: 665

  13. Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile

    著者: Manuel Tsiang, G.S. Jones, Joshua Goldsmith, Andrew Mulato, Derek Hansen, Elaine Kan, Luong Tsai, Rujuta A. Bam, George Stepan, Kirsten M. Stray, Anita Niedziela‐Majka, Stephen R. Yant, Helen Yu, George Kukolj, Tomáš Cihlář, Scott E. Lazerwith, Kirsten White, Haolun Jin - Antimicrobial Agents and Chemotherapy 2016 被引用: 283

  14. Lenacapavir: A Novel, Potent, and Selective First-in-Class Inhibitor of HIV-1 Capsid Function Exhibits Optimal Pharmacokinetic Properties for a Long-Acting Injectable Antiretroviral Agent

    著者: Raju Subramanian, Jennifer Tang, Jim Zheng, Bing Lu, Kelly Wang, Stephen R. Yant, George Stepan, Andrew Mulato, Helen Yu, Scott D. Schroeder, M. Naveed Shaik, Renu Singh, Scott A. Wolckenhauer, Anne Chester, Winston C. Tse, Anna Chiu, Martin S. Rhee, Tomáš Cihlář, William Rowe, Bill J. Smith - Molecular Pharmaceutics 2023 被引用: 48

  15. Current status and prospects of HIV treatment

    著者: Tomáš Cihlář, Marshall W. Fordyce - Current Opinion in Virology 2016 被引用: 332

  16. Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine C-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV

    著者: Richard L. Mackman, Hon C. Hui, Michel Perron, Eisuke Murakami, Christopher A. Palmiotti, Gary Lee, Kirsten M. Stray, Lijun Zhang, Bindu Goyal, Kwon Soo Chun, Daniel Byun, Dustin S. Siegel, Scott P. Simonovich, Venice Du Pont, Jared Pitts, Darius Babusis, Arya Vijjapurapu, Xianghan Lu, Cynthia Kim, Xiaofeng Zhao, Julie Chan, Bin Ma, Diane S. Lye, Adelle A. Vandersteen, Sarah Wortman, Kimberly T. Barrett, Maria M. Toteva, Robert Jordan, Raju Subramanian, John P. Bilello, Tomáš Cihlář - Journal of Medicinal Chemistry 2021 被引用: 90

  17. Remdesivir (GS-5734) Is Efficacious in Cynomolgus Macaques Infected With Marburg Virus

    著者: Danielle Porter, Jessica M. Weidner, Laura Gomba, Roy Bannister, Christiana Blair, Robert Jordan, Jay Wells, Kelly S. Wetzel, Nicole L. Garza, Sean Van Tongeren, Ginger Donnelly, Jesse Steffens, Alicia M. Moreau, Jeremy J. Bearss, Eric Lee, Sina Bavari, Tomáš Cihlář, Travis K. Warren - The Journal of Infectious Diseases 2020 被引用: 81

  18. Expanded profiling of Remdesivir as a broad-spectrum antiviral and low potential for interaction with other medications in vitro

    著者: Sheli R. Radoshitzky, Patrick L. Iversen, Xianghan Lu, Jing Zou, Suzanne J. F. Kaptein, Kelly S. Stuthman, Sean A. Van Tongeren, Jesse Steffens, Ruoyu Gong, Hoa Truong, Annapurna Sapre, Huiling Yang, Xiaodong Xie, Jia Jun Chia, Zhijuan Song, Stacey M. Leventhal, Josolyn Chan, Alex Shornikov, Xin Zhang, David Cowfer, Helen Yu, Travis K. Warren, Tomáš Cihlář, Danielle Porter, Johan Neyts, Pei‐Yong Shi, Jay Wells, John P. Bilello, Joy Y. Feng - Scientific Reports 2023 被引用: 71

  19. Oral administration of obeldesivir protects nonhuman primates against Sudan ebolavirus

    著者: Robert W. Cross, Courtney Woolsey, Victor C. Chu, Darius Babusis, Roy Bannister, Meghan S. Vermillion, Romas Geleziunas, Kimberly T. Barrett, Elaine Bunyan, Anh-Quan Nguyen, Tomáš Cihlář, Danielle Porter, Abhishek N. Prasad, Daniel J. Deer, Viktoriya Borisevich, Krystle N. Agans, Jasmine Martinez, Mack B. Harrison, Natalie S. Dobias, Karla A. Fenton, John P. Bilello, Thomas W. Geisbert - Science 2024 被引用: 36

  20. Remdesivir and GS-441524 Retain Antiviral Activity against Delta, Omicron, and Other Emergent SARS-CoV-2 Variants

    著者: Jared Pitts, Jiani Li, Jason K. Perry, Venice Du Pont, Nicholas C. Riola, Lauren Rodriguez, Xianghan Lu, Chaitanya Kurhade, Xuping Xie, Grégory Camus, Savrina Manhas, Ross Martin, Pei‐Yong Shi, Tomáš Cihlář, Danielle Porter, Hongmei Mo, Evguenia Maiorova, John P. Bilello - Antimicrobial Agents and Chemotherapy 2022 被引用: 76

  21. Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets

    著者: Robert M. Cox, Josef D. Wolf, Carolin M. Lieber, Julien Sourimant, Michelle J. Lin, Darius Babusis, Venice DuPont, Julie Chan, Kim Barrett, Diane S. Lye, Rao Kalla, Kwon Soo Chun, Richard L. Mackman, Chengjin Ye, Tomáš Cihlář, Luis Martínez‐Sobrido, Alexander L. Greninger, John P. Bilello, Richard K. Plemper - Nature Communications 2021 被引用: 131

  22. Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice

    著者: Alexandra Schäfer, David R. Martinez, John J. Won, Rita M. Meganck, Fernando R. Moreira, Ariane J. Brown, Kendra L. Gully, Mark R. Zweigart, William S. Conrad, Samantha R. May, Stephanie Dong, Rao Kalla, Kwon Soo Chun, Venice Du Pont, Darius Babusis, Jennifer Tang, Eisuke Murakami, Raju Subramanian, Kimberly T. Barrett, Blake J. Bleier, Roy Bannister, Joy Y. Feng, John P. Bilello, Tomáš Cihlář, Richard L. Mackman, Stephanie A. Montgomery, Ralph S. Baric, Timothy P. Sheahan - Science Translational Medicine 2022 被引用: 83

  23. No virologic resistance to bulevirtide monotherapy detected in patients through 24 weeks treatment in phase II and III clinical trials for chronic hepatitis delta

    著者: Julius Hollnberger, Yang Liu, Simin Xu, Silvia Chang, Ross Martin, Savrina Manhas, Thomas Aeschbacher, Bin Han, Tahmineh Yazdi, Lindsey May, Dong Han, Alex Shornikov, John F. Flaherty, Dmitry Manuilov, Vithika Suri, Tarik Asselah, Pietro Lampertico, Heiner Wedemeyer, Soo Aleman, Christopher J. Richards, Roberto Mateo, Evguenia Maiorova, Tomáš Cihlář, Hongmei Mo, Stephan Urban - Journal of Hepatology 2023 被引用: 23

  24. Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase

    著者: Ariane J. Brown, John J. Won, Rachel L. Graham, Kenneth H. Dinnon, Amy Sims, Joy Y. Feng, Tomáš Cihlář, Mark R. Denison, Ralph S. Baric, Timothy P. Sheahan - Antiviral Research 2019 被引用: 531