W.H. Irwin McLean
1991–2021 年に発表
- 128
- 論文数
- 30,650
- 被引用数
- 100
- h 指数
- 128
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine59.7%
- Biochemistry, Genetics and Molecular Biology26.6%
- Immunology and Microbiology6.7%
- Neuroscience1.8%
- Pharmacology, Toxicology and Pharmaceutics1.5%
- Health Professions0.7%
- その他3%
トピック
- Dermatology and Skin Diseases14%
- Allergic Rhinitis and Sensitization7%
- Asthma and respiratory diseases5.4%
- Skin and Cellular Biology Research5.3%
- Food Allergy and Anaphylaxis Research4.6%
- Psoriasis: Treatment and Pathogenesis3.3%
- その他60.4%
共著者
- Alan D. Irvine40
- Frances J.D. Smith30
- Aileen Sandilands27
- Linda Campbell19
- Sara Brown16
- Haihui Liao15
- E. Birgitte Lane14
- Yiwei Zhao14
- Gráinne M. O’Regan13
- Colin N.A. Palmer12
- John A. McGrath10
- Gideon Lack9
- Robin A.J. Eady9
- Colin S. Munro8
- Hansjörg Baurecht8
- Irene M. Leigh8
- Jouni Uitto8
- Masashi Akiyama8
- Sanja Kežić8
- Heather J. Cordell7
- Karin Kroboth7
- Stephan Weidinger7
- Alan Evans6
- Carsten Flohr6
全論文
- Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis
著者: Colin N A Palmer, Alan D. Irvine, Ana Terron-Kwiatkowski, Yiwei Zhao, Haihui Liao, Simon P. Lee, David Goudie, Aileen Sandilands, Linda Campbell, Frances J.D. Smith, Gráinne M. O’Regan, Rosemarie M. Watson, Joanne E. Cecil, Sherri J. Bale, John G. Compton, John J DiGiovanna, Philip Fleckman, Sue Lewis‐Jones, Gehan Arseculeratne, Ann Sergeant, Colin S. Munro, Brahim El Houate, Ken McElreavey, Liselotte Brydensholt Halkjær, Hans Bisgaard, Somnath Mukhopadhyay, W.H. Irwin McLean - Nature Genetics 2006 被引用: 2,950
- Filaggrin Mutations Associated with Skin and Allergic Diseases
著者: Alan D. Irvine, W.H. Irwin McLean, Donald Y.M. Leung - New England Journal of Medicine 2011 被引用: 1,204
- Filaggrin in the frontline: role in skin barrier function and disease
著者: Aileen Sandilands, Calum Sutherland, Alan D. Irvine, W.H. Irwin McLean - Journal of Cell Science 2009 被引用: 872
- A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
著者: Amy Strange, Gavin Band, Gavin Band, Matti Pirinen, Chris C. A. Spencer, Céline Bellenguez, Colin L. Freeman, Anna Rautanen, Zhan Su, Francesca Capon, Christopher G. Mathew, Michael E. Weale, Alexandros Onoufriadis, Richard C. Trembath, Michael H. Allen, Alexandros Onoufriadis, Jo Knight, Catherine Smith, Frank O. Nestlé, Richard C. Trembath, Jo Knight, Frank O. Nestlé, Anne Barton, Jane Worthington, Joost Schalkwijk, Patrick L.J.M. Zeeuwen, Judith G.M. Bergboer, Jenefer M. Blackwell, Elvira Bramon, Emma Gray, Suzannah J. Bumpstead, Sarah Hunt, Simon Potter, Sarah Edkins, Cordelia Langford, Leena Peltonen, Panos Deloukas, Juan P. Casas, Michael J. Cork, Rachid Tazi‐Ahnini, Aiden Corvin, Gilean McVean, Alexander Dilthey, Gil McVean, Loukas Moutsianas, Stephen Leslie, Audrey Duncanson, Xavier Estivill, Eva Riveira‐Muñoz, Brian Kirby, Oliver FitzGerald, Emiliano Giardina, Giuseppe Novelli, Wolfgang Weger, Angelika Hofer, Wolfgang Salmhofer, André Reis, Ulrike Hüffmeier, Alan D. Irvine, Janusz Jankowski, Jesús Lascorz, A. David Burden, Joyce Leman, Katarina Wolk, Lotus Mallbris, Mona Ståhle, Hugh S. Markus, W.H. Irwin McLean, Lena Samuelsson, Colin N A Palmer, Carlo Perricone, Robert Plomin, Rotraut Mößner, Åsa Torinsson Naluai, Lena Samuelsson, Heiko Traupe, Carlo Perricone, Robert Plomin, Ramón M. Pujol, Adrian Hayday, Stephen Sawcer, Juha Kere, Catherine Smith, Heiko Traupe - Nature Genetics 2010 被引用: 1,058
- Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention
著者: Eric L. Simpson, Joanne R Chalmers, Jon M. Hanifin, Kim S Thomas, Michael J. Cork, W.H. Irwin McLean, Sara Brown, Zunqiu Chen, Yiyi Chen, Hywel C Williams - Journal of Allergy and Clinical Immunology 2014 被引用: 718
- Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy
著者: Helen A. Brough, Andrew H. Liu, Scott H. Sicherer, Kerry Makinson, Abdel Douiri, Sara Brown, Alick Stephens, W.H. Irwin McLean, Victor Turcanu, Robert A. Wood, Stacie M. Jones, Wesley Burks, Peter Dawson, Donald M. Stablein, Hugh A. Sampson, Gideon Lack - Journal of Allergy and Clinical Immunology 2014 被引用: 344
- Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year
著者: Elizabeth A. Kennedy, Jennifer Connolly, Jonathan O’B Hourihane, Padraic G. Fallon, W.H. Irwin McLean, Deirdre M. Murray, Jay‐Hyun Jo, Julia A. Segre, Heidi H. Kong, Alan D. Irvine - Journal of Allergy and Clinical Immunology 2016 被引用: 345
- Gut microbiota development during infancy: Impact of introducing allergenic foods
著者: Tom Marrs, Jay‐Hyun Jo, Michael R. Perkin, Damian Rivett, Adam A. Witney, Kenneth D. Bruce, Kirsty Logan, Joanna Craven, Suzana Radulović, Serge A. Versteeg, Ronald van Ree, W.H. Irwin McLean, David P. Strachan, Gideon Lack, Heidi H. Kong, Carsten Flohr - Journal of Allergy and Clinical Immunology 2021 被引用: 111
- Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema
著者: Aileen Sandilands, Ana Terron-Kwiatkowski, Peter Hull, Gráinne M. O’Regan, Timothy Clayton, Rosemarie M. Watson, Thomas Carrick, Alan Evans, Haihui Liao, Yiwei Zhao, Linda Campbell, Matthias Schmuth, Robert Gruber, Andreas Janecke, Peter M. Elias, Maurice A. M. Van Steensel, Ivo F. Nagtzaam, Michel van Geel, Peter M. Steijlen, Colin S. Munro, Daniel G. Bradley, Colin N A Palmer, Frances J.D. Smith, W.H. Irwin McLean, Alan D. Irvine - Nature Genetics 2007 被引用: 664
- Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris
著者: Frances J.D. Smith, Alan D. Irvine, Ana Terron-Kwiatkowski, Aileen Sandilands, Linda Campbell, Yiwei Zhao, Haihui Liao, Alan Evans, David Goudie, Sue Lewis‐Jones, Gehan Arseculeratne, Colin S. Munro, Ann Sergeant, Gráinne M. O’Regan, Sherri J. Bale, John G. Compton, John J DiGiovanna, Richard B. Presland, Philip Fleckman, W.H. Irwin McLean - Nature Genetics 2006 被引用: 1,031
- Levels of filaggrin degradation products are influenced by both filaggrin genotype and atopic dermatitis severity
著者: S. Kezic, Gráinne M. O’Regan, Nico L. H. Yau, Aileen Sandilands, H. Chen, Linda Campbell, Karin Kroboth, Roger Watson, Marion Rowland, W.H. Irwin McLean, Alan D. Irvine - Allergy 2011 被引用: 291
- Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency
著者: Sanja Kežić, Gráinne M. O’Regan, René Lutter, Ivone Jakaša, Ellen S. Koster, Sean P. Saunders, Peter J. Caspers, P. M. J. H. Kemperman, Gerwin J. Puppels, Aileen Sandilands, Huijia Chen, Linda Campbell, Karin Kroboth, Rosemarie Watson, Padraic G. Fallon, W.H. Irwin McLean, Alan D. Irvine - Journal of Allergy and Clinical Immunology 2012 被引用: 267
- The Human Intermediate Filament Database: comprehensive information on a gene family involved in many human diseases
著者: Ildikó Szeverényi, Andrew Cassidy, Cheuk Wang Chung, Bernett T. K. Lee, John Common, Stephen C. Ogg, Huijia Chen, Shu Yin Sim, Walter L.P. Goh, Kee Woei Ng, John Simpson, Li Lian Chee, Goi Hui Eng, Bin Li, Declan P. Lunny, Danny Chuon, Aparna Venkatesh, Kian Hoe Khoo, W.H. Irwin McLean, Yun Ping Lim, E. Birgitte Lane - Human Mutation 2007 被引用: 372
- One Remarkable Molecule: Filaggrin
著者: Sara Brown, W.H. Irwin McLean - Journal of Investigative Dermatology 2011 被引用: 517
- Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting
著者: Liat Samuelov, Ofer Sarig, Robert M. Harmon, Debora Rapaport, Akemi Ishida‐Yamamoto, Ofer Isakov, Jennifer L. Koetsier, Andrea Gat, Ilan Goldberg, Reuven Bergman, Ronen Spiegel, Ori Eytan, Shamir Geller, Sarit Peleg, Noam Shomron, Christabelle S.M. Goh, Neil Wilson, Frances J.D. Smith, Elizabeth Pöhler, Michael A. Simpson, W.H. Irwin McLean, Alan D. Irvine, Mia Horowitz, John A. McGrath, Kathleen J. Green, Eli Sprecher - Nature Genetics 2013 被引用: 334
- Systemic and stratum corneum biomarkers of severity in infant atopic dermatitis include markers of innate and T helper cell‐related immunity and angiogenesis
著者: Maeve A. McAleer, Ivone Jakaša, Guillem Hurault, Pouya Sarvari, W.H. Irwin McLean, Reiko Tanaka, S. Kezic, Alan D. Irvine - British Journal of Dermatology 2018 被引用: 105
- Peanut allergy: Effect of environmental peanut exposure in children with filaggrin loss-of-function mutations
著者: Helen A. Brough, Angela Simpson, Kerry Makinson, Jenny Hankinson, Sara Brown, Abdel Douiri, Danielle Belgrave, Martín Penagos, Alick Stephens, W.H. Irwin McLean, Victor Turcanu, Nicolaos Nicolaou, Adnan Čustović, Gideon Lack - Journal of Allergy and Clinical Immunology 2014 被引用: 284
- Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis
著者: Toshifumi Nomura, Aileen Sandilands, Masashi Akiyama, Haihui Liao, Alan Evans, Kaori Sakai, Mitsuhito Ota, Hisashi Sugiura, Kazuo Yamamoto, Hiroshi Satō, Colin N.A. Palmer, Frances J.D. Smith, W.H. Irwin McLean, Hiroshi Shimizu - Journal of Allergy and Clinical Immunology 2007 被引用: 272
- Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy
著者: Sara Brown, Yuka Asai, Heather J. Cordell, Linda Campbell, Yiwei Zhao, Haihui Liao, Kate Northstone, John Henderson, Reza Alizadehfar, Moshe Ben‐Shoshan, Kenneth Morgan, Graham Roberts, L. J. Masthoff, Suzanne G.M.A. Pasmans, Peter C. van den Akker, Cisca Wijmenga, Jonathan O’B Hourihane, Colin N.A. Palmer, Gideon Lack, Ann E. Clarke, Peter Hull, Alan D. Irvine, W.H. Irwin McLean - Journal of Allergy and Clinical Immunology 2011 被引用: 473
- Clumping Factor B Promotes Adherence of Staphylococcus aureus to Corneocytes in Atopic Dermatitis
著者: Orla M. Fleury, Maeve A. McAleer, Cécile Feuillie, Cécile Formosa‐Dague, Emily A. Sansevere, Désirée E. Bennett, Aisling M. Towell, W.H. Irwin McLean, Sanja Kežić, D. Ashley Robinson, Padraic G. Fallon, Timothy J. Foster, Yves F. Dufrêne, Alan D. Irvine, Joan A. Geoghegan - Infection and Immunity 2017 被引用: 108
- Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis
著者: Jonathan Martínez‐Fábregas, Alan R. Prescott, Sander van Kasteren, Deena M. Leslie Pedrioli, W.H. Irwin McLean, Anna Moles, Thomas Reinheckel, Valeria Poli, Colin Watts - Nature Communications 2018 被引用: 87
- Intermediate Filament Proteins and Their Associated Diseases
著者: M. Bishr Omary, Pierre A. Coulombe, W.H. Irwin McLean - New England Journal of Medicine 2004 被引用: 478
- Filaggrin loss-of-function mutations are associated with early-onset eczema, eczema severity and transepidermal water loss at 3 months of age
著者: Carsten Flohr, Kerry England, Suzana Radulović, W.H. Irwin McLean, Linda Campbell, Juliet N. Barker, Michael R. Perkin, Gideon Lack - British Journal of Dermatology 2010 被引用: 252
- Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects
著者: Sean P. Saunders, Christabelle S.M. Goh, Sara Brown, Colin N.A. Palmer, Rebecca M. Porter, Christian Cole, Linda Campbell, Marek Gierliński, Geoffrey J. Barton, Georg Schneider, Allan Balmain, Alan R. Prescott, Stephan Weidinger, Hansjörg Baurecht, Michael Kabesch, Christian Gieger, Young‐Ae Lee, Roger Tavendale, Somnath Mukhopadhyay, Stephen W. Turner, Vishnu Madhok, Frank Sullivan, Caroline L. Relton, John Burn, Simon Meggitt, Catherine Smith, Michael Allen, Jonathan N.W. N. Barker, Nick J. Reynolds, Heather J. Cordell, Alan D. Irvine, W.H. Irwin McLean, Aileen Sandilands, Padraic G. Fallon - Journal of Allergy and Clinical Immunology 2013 被引用: 160
