SQR mediates therapeutic effects of H 2 S by targeting mitochondrial electron transport to induce mitochondrial uncoupling

著者: Jia Jia, Zichuang Wang, Minjie Zhang, Caiyun Huang, Yanmei Song, XU Fu-you, Jingyu Zhang, Jie Li, Meijun He, Yuyao Li, Gui‐Zhen Ao, Hong Chengjiao, Yongjun Cao, Y. Eugene Chin, Zichun Hua, Jian Cheng - Science Advances 2020 被引用: 90

S signaling and therapeutic effects by targeting mitochondrial electron transport to induce mitochondrial uncoupling. Moreover, SQR is a previously unrecognized target for developing non-protonophore uncouplers with broad clinical implications.