T H 17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional identity

著者: Stacey N. Harbour, Daniel DiToro, Steven Witte, Carlene L. Zindl, Min Gao, Trenton R. Schoeb, Gareth W. Jones, Simon A. Jones, Robin D. Hatton, Casey T. Weaver - Science Immunology 2020 被引用: 140

Ongoing classic IL-6 receptor signaling is required to maintain the T H 17 program, acting upstream of IL-23 to sustain RORγt expression.