The Prevention and Treatment of Missing Data in Clinical Trials

著者: Roderick J. A. Little, Ralph B. D’Agostino, Michael L. Cohen, Kay Dickersin, Scott S. Emerson, John T. Farrar, Constantine Frangakis, Joseph W. Hogan, Geert Molenberghs, Susan A. Murphy, James D. Neaton, Andrea Rotnitzky, Daniel O. Scharfstein, Weichung Joe Shih, Jay P. Siegel, Hal S. Stern - New England Journal of Medicine, NEJM 2012 被引用: 1,891

Missing data in clinical trials can have a major effect on the validity of the inferences that can be drawn from the trial. This article reviews methods for preventing missing data and, failing that, dealing with data that are missing.