CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism

著者: Andrea Piunti, Edwin R. Smith, Marc A. Morgan, Michal Ugarenko, Natalia Khaltyan, Kathryn A. Helmin, Caila Ryan, David C. Murray, Ryan Rickels, Bahar D. Yilmaz, Emily J. Rendleman, Jeffrey N. Savas, Benjamin D. Singer, Serdar E. Bulun, Ali Shilatifard - Science Advances 2019 被引用: 120

as the potential interlocutor between DNA methylation and PRC2 activity. We raise the possibility that similar regulatory mechanisms could exist for other methyltransferase complexes such as Trithorax/COMPASS.