Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation

著者: Sarah Mundt, Dunja Mrdjen, Sebastian G. Utz, Melanie Greter, Bettina Schreiner, Burkhard Becher - Science Immunology 2019 被引用: 241

cells in vivo. We found a population of conventional dendritic cells, but not border-associated macrophages or microglia, to be essential for licensing T cells to initiate neuroinflammation.