From peptides to proteins: coiled-coil tetramers to single-chain 4-helix bundles

著者: Elise A. Naudin, Katherine I. Albanese, Abigail J. Smith, B. Mylemans, Emily G. Baker, Orion D. Weiner, David Andrews, Natalie J. Tigue, Nigel J. Savery, Derek N. Woolfson - Chemical Science 2022 被引用: 25

. All of the assembled designs are confirmed in aqueous solution using biophysical methods, and ultimately by determining high-resolution X-ray crystal structures. Our route from peptides to proteins provides an understanding of the role of each residue in each design.