Suppression of USP8 sensitizes cells to ferroptosis via SQSTM1/p62-mediated ferritinophagy

著者: Lihong Liu, Birong Zheng, Manhui Luo, Jie Du, Fang Yang, Chuanxin Huang, Zengyi Ma, Chunmei Li, Deyin Guo, Hong Peng - Protein & Cell 2022 被引用: 26

Ferroptosis is a newly discovered form of regulated cell death characterized by increased intracellular iron accumulation and subsequent lipid peroxidation Studies have revealed that ferroptosis plays an important role in multiple physiological and pathological processes including degenerative diseases, carcinogenesis, and cancer immunotherapy