Complement-Activating Anti-HLA Antibodies in Kidney Transplantation: Allograft Gene Expression Profiling and Response to Treatment

著者: Carmen Lefaucheur, Denis Viglietti, Luis Hidalgo, Lloyd E. Ratner, Serena M. Bagnasco, Ibrahim Batal, Olivier Aubert, Babak J. Orandi, Federico Oppenheimer, Oriol Bestard, Paolo Rigotti, Anna Varberg Reisæter, Nassim Kamar, Yvon Lebranchu, Jean–Paul Duong Van Huyen, Patrick Bruneval, Denis Glotz, Christophe Legendre, Jean‐Philippe Empana, Xavier Jouven, Dorry L. Segev, Robert A. Montgomery, Adriana Zeevi, Philip F. Halloran, Alexandre Loupy - Journal of the American Society of Nephrology 2017 被引用: 115

=0.65). In conclusion, circulating complement-activating anti-HLA DSAs are associated with a specific histomolecular kidney allograft rejection phenotype that can be abrogated by complement inhibition.