著者: Club Jules Gonin , Deutsche Ophthalmologische Gesellschaft , Vanessa Vera , Markus Lenzhofer , Keith Barton , Ingeborg Stalmans , For , P Lichter , D Musch , B Gillespie , K Guire , N Janz , P Wren , R Mills , Study Cigts , Group , L Feiner , J Piltz-Seymour , H Jampel , D Musch , B Gillespie , P Lichter , M Wright , K Guire , S Zahid , D Musch , L Niziol , P Lichter , S Gedde , W Feuer , W Shi , K Lim , K Barton , S Goyal , Iik Ahmed , J Brandt , V Vera , C Horvath , T Samuelson , L Katz , J Wells , Y Duh , J Giamporcaro , S Vold , Iik Ahmed , E Craven , C Mattox , R Stamper , M Packer , R Brown , T Ianchulev , J Caprioli , J Kim , D Friedman , T Kiang , M Moster , Parrish Rk 2nd , E Rorer , T Samuelson , M Tarver , K Singh , M Eydelman , De Gregorio , A Pedrotti , E Russo , L Morselli , S , A Galal , A Bilgic , R Eltanamly , A Osman , F Hengerer , T Kohnen , M Mueller , Conrad Hengerer , I , C Sng , J Wang , S Hau , H Htoon , K Barton , K Mansouri , J Guidotti , H Rao , A Ouabas , D 'alessandro , E Roy , S Mermoud , A , S Tan , A Walkden , L Au , A Ibez-Muoz , V Soto-Biforcos , M Chacn-Gonzlez , O Ra-Galisteo , Arrieta-Los Santos , A , Lizuain-Abadia Me , Del Ro Mayor , J , K Mansouri , K Gillmann , H Rao , J Guidotti , A Mermoud , Parrish Rk 2nd , D Minckler , D Lam , N Pfeiffer , P Rojanapongpun , R Armstrong , B Rosner , R Glynn , M Lee , D Grover , W Flynn , K Bashford , R Lewis , Y Duh , R Nangia , B Niksch , M Schlenker , H Gulamhusein , Conrad Hengerer , I Somers , A Lenzhofer , M Stalmans , I Reitsamer , H Hengerer , F Ahmed , Iik , S Ozal , O Kaplaner , B Basar , H Guclu , E Ozal , R Widder , T Dietlein , S Dinslage , P Kuhnrich , C Rennings , G Rossler , Prez-Torregrosa Vt , A Olate-Prez , M Cerd-Ibez , A Gargallo-Benedicto , V Osorio-Alayo , A Barreiro-Rego , A Duch-Samper , A Fea , R Spinetta , Pml Cannizzo , G Consolandi , C Lavia , V Aragno , F Germinetti , T Rolle , B Hohberger , U Welge-Len , R Lmmer , E Craven , L Katz , J Wells , J Giamporcaro , B Song , M Ramanathan , E Morales , S Law , J Giaconi , A Coleman , J Caprioli , L Jung , C Isida-Llerandi , G Lazcano-Gomez , J Soohoo , M Kahook , S Murthy , K Damji , Y Pan , W Hodge , S Cillino , Di Pace , F Casuccio , A Calvaruso , L Morreale , D Vadala , M Lodato , G , S Kuroda , T Mizoguchi , H Terauchi , M Nagata , M Guggenbach , D Mojon , M Bhnke , J D E R I C K R J , E V A N S , B , C Yu , N Chong , R Caesar , M Boodhoo , R Condon , T Chang , D Budenz , A Liu , W Kim , T Dang , C Li , A Iwach , S Radhakrishnan , K Singh , S Mansberger , M Gordon , H Jampel , A Bhorade , J Brandt , B Wilson , M Kass , M Slabaugh , K Bojikian , D Moore , P Chen , S Gedde , L Herndon , J Brandt , D Budenz , W Feuer , J Schiffman , S Gedde , J Schiffman , W Feuer , L Herndon , J Brandt , D Budenz , S Khouri , G Huang , L Huang , M Pakravan , H Esfandiari , S Yazdani , A Douzandeh , N Amouhashemi , M Yaseri , P Pakravan , V Vera , Iik Ahmed , I Stalmans , H Reitsamer , L Vijaya , Manish Ronnie , G Shantha , B , A Nguyen , N Fatehi , P Romero , A Miraftabi , E Kim , E Morales , J Giaconi , A Coleman , S Law , J Caprioli , K Nouri-Mahdavi , C Tan , P Chew , W Lum , C Chee , J Wong , L Yip , C Tan , P Chew - Graefe s Archive for Clinical and Experimental Ophthalmology 2013 被引用: 400
Purpose To evaluate the effectiveness of an ab interno subconjunctival gelatin implant as primary surgical intervention in reducing intraocular pressure (IOP) and IOP-lowering medication count in medically uncontrolled moderate primary openangle glaucoma (POAG). Methods In this prospective, non-randomized, open-label, multicenter, 2-year study, eyes with medicated baseline IOP 18-33 mmHg on 1-4 topical medications were implanted with (phaco + implant) or without (implant alone) phacoemulsification. Changes in mean IOP and medication count at months 12 (primary outcomes) and 24, clinical success rate (eyes [%] achieving 20% IOP reduction from baseline on the same or fewer medications without glaucoma-related secondary surgical intervention), intraoperative complications, and postoperative adverse events were assessed.
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