COVID-19 Mortality and Progress Toward Vaccinating Older Adults — World Health Organization, Worldwide, 2020–2022

著者: Man Kai Wong, Donald Brooks, Juniorcaius Ikejezie, Marta Gacic-Dobo, Laure Dumolard, Yoann Nedelec, Claudia Steulet, Zyleen Kassamali, Ayşe Açma, Brian Ngongheh Ajong, Sandra Adele, Maya Allan, Homa Attar Cohen, Adedoyin Awofisayo-Okuyelu, Finlay Campbell, Veronica Cristea, S. de Barros, Ntokwo Vabi Edward, Aura R. Escobar Corado Waeber, Tondri Noe Guinko, Henry Laurenson‐Schafer, Mostafa Mahran, Raquel Medialdea‐Carrera, Samuel Mesfin, Emily Meyer, Alessandro Miglietta, Bernadette Basuta Mirembe, Maribeth Mitri, Ingrid Hammermeister Nezu, Stephanie Ngai, Ojong Ojong Ejoh, Sydel R. Parikh, Emilie Peron, Nikola Sklenovská, Savine Stoitsova, Kazuki Shimizu, Eri Togami, Yeo Won Jin, Boris Pavlin, Ryan T. Novak, Olivier le Polain de Waroux, James A. Fuller, Abdi Rahman Mahamud, Ann Lindstrand, Bradley S. Hersh, Katherine L. O’Brien, Maria D. Van Kerkhove - MMWR Morbidity and Mortality Weekly Report 2023 被引用: 113

with the goal of 100% coverage with a complete COVID-19 vaccination series** for at-risk populations. Using available public data on COVID-19 mortality (reported deaths and model estimates) for 2020 and 2021 and the most recent reported COVID-19 vaccination coverage data from WHO, investigators performed descriptive analyses to examine age-specific mortality and global vaccination rollout among older adults (as defined by each country), stratified by country World Bank income status. Data quality and COVID-19 death reporting frequency varied by data source; however, persons aged ≥60 years accounted for >80% of the overall COVID-19 mortality across all income groups, with upper- and lower-middle-income countries accounting for 80% of the overall estimated excess mortality. Effective COVID-19 vaccines were authorized for use in December 2020, with global supply scaled up sufficiently to meet country needs by late 2021 (6). COVID-19 vaccines are safe and highly effective in reducing severe COVID-19, hospitalizations, and mortality (7,8); nevertheless, country-reported median completed primary series coverage among adults aged ≥60 years only reached 76% by the end of 2022, substantially below the WHO goal, especially in middle- and low-income countries. Increased efforts are needed to increase primary series and booster dose coverage among all older adults as recommended by WHO and national health authorities.