Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy

著者: Katherine S. Yang, Hyungsoon Im, Seonki Hong, Ilaria Pergolini, Andres Fernandez del Castillo, Rui Wang, Susan M. Clardy, Chen-Han Huang, Craig Pille, Soldano Ferrone, Robert Yang, Cesar M. Castro, Hakho Lee, Carlos Fernández del Castillo, Ralph Weissleder - Science Translational Medicine 2017 被引用: 291

signature of tEVs offered higher sensitivity, specificity, and accuracy than the existing serum marker (CA 19-9) or single-tEV marker analyses. This approach should improve the diagnosis of pancreatic cancer.