Differences in the gut microbiome by physical activity and BMI among colorectal cancer patients.

著者: Caroline Himbert, W. Zac Stephens, Biljana Gigic, Sheetal Hardikar, Andreana N. Holowatyj, Tengda Lin, Jennifer Ose, Eric A. Swanson, Anjelica Ashworth, Christy A. Warby, Anita R. Peoples, David A. Nix, Jolanta Jedrzkiewicz, Mary P. Bronner, Bartley Pickron, Courtney L. Scaife, Jessica N. Cohan, Petra Schrotz‐King, Nina Habermann, Juergen Boehm, Meredith A.J. Hullar, Jane C. Figueiredo, Adetunji T. Toriola, Erin M. Siegel, Christopher I. Li, Alexis Ulrich, David Shibata, Kenneth M. Boucher, Lyen C. Huang, Martin Schneider, June L. Round, Cornelia M. Ulrich - National Institutes of Health 2022 被引用: 22

) were differentially abundant across physical activity and BMI groups. This is the first evidence for associations of physical activity with gut microbiome diversity and abundances, directly among colorectal cancer patients. Our results indicate that physical activity may offset gut microbiome dysbiosis due to obesity. Alterations in gut microbiota may contribute mechanistically to the energy balance-colorectal cancer link and impact clinical outcomes.