Enteric glial cells favor accumulation of anti-inflammatory macrophages during the resolution of muscularis inflammation

著者: Michelle Stakenborg, Saeed Abdurahiman, Veronica De Simone, Gera Goverse, Nathalie Stakenborg, Lies van Baarle, Qin Wu, Dimitri Pirottin, Jung‐Seok Kim, Louise Chappell‐Maor, Isabel Pintelon, Sofie Thys, Emilie Pollenus, Louis Boon, Philippe E. Van den Steen, Marlene M. Hao, Jo A. Van Ginderachter, Guy E. Boeckxstaens, Jean‐Pierre Timmermans, Steffen Jung, Thomas Marichal, Sales Ibiza, Gianluca Matteoli - Mucosal Immunology 2022 被引用: 52

Mφs and EGC proliferation during muscularis inflammation. Our study provides a comprehensive insight into pro-resolving Mφ differentiation and their regulators during muscularis inflammation. We deepened our understanding in the interaction between EGCs and Mφs, thereby highlighting pro-resolving Mφ differentiation as a potential novel therapeutic strategy for the treatment of intestinal inflammation.