Ebola Vaccination Using a DNA Vaccine Coated on PLGA‐PLL/γPGA Nanoparticles Administered Using a Microneedle Patch

著者: Hung‐Wei Yang, Ling Ye, Xin Dong Guo, Chinglai Yang, Richard W. Compans, Mark R. Prausnitz - Advanced Healthcare Materials 2016 被引用: 120

Ebola DNA vaccine is incorporated into PLGA-PLL/γPGA nanoparticles and administered to skin using a microneedle (MN) patch. The nanoparticle delivery system increases vaccine thermostability and immunogenicity compared to free vaccine. Vaccination by MN patch produces stronger immune responses than intramuscular administration. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.