A Novel Sparse Compositional Technique Reveals Microbial Perturbations

著者: Cameron Martino, James T. Morton, Clarisse Marotz, Luke Thompson, Anupriya Tripathi, Rob Knight, Karsten Zengler - mSystems 2019 被引用: 612

By accounting for the sparse compositional nature of microbiome data sets, robust Aitchison PCA can yield high discriminatory power and salient feature ranking between microbial niches. The software to perform this analysis is available under an open-source license and can be obtained at https://github.com/biocore/DEICODE; additionally, a QIIME 2 plugin is provided to perform this analysis at https://library.qiime2.org/plugins/deicode/.