Proteolysis-targeting chimera (PROTAC) delivery system: advancing protein degraders towards clinical translation

著者: Yu Chen, Ira Tandon, William J. Heelan, Yixin Wang, Weiping Tang, Quanyin Hu - Chemical Society Reviews 2022 被引用: 273

degradation efficacy of PROTACs through delivery strategies, outline design principles for PROTAC-based delivery systems, discuss the current challenges with PROTACs, and outlook future opportunities in this field.