Bimodal neuromodulation combining sound and tongue stimulation reduces tinnitus symptoms in a large randomized clinical study

著者: Brendan J. Conlon, Berthold Langguth, Caroline Hamilton, Stephen G. Hughes, Emma Meade, Ciara O Connor, Martin Schecklmann, Deborah A. Hall, Sven Vanneste, Sook Ling Leong, Thavakumar Subramaniam, Shona D’Arcy, Hubert H. Lim - Science Translational Medicine 2020 被引用: 110

< 0.001). Therapeutic improvements continued for 12 months after treatment for specific bimodal stimulation settings, which had not previously been demonstrated in a large cohort for a tinnitus intervention. The treatment also achieved high compliance and satisfaction rates with no treatment-related serious adverse events. These positive therapeutic and long-term results motivate further clinical trials toward establishing bimodal neuromodulation as a clinically recommended device treatment for tinnitus.