Hypothalamic regulation of regionally distinct adult neural stem cells and neurogenesis
Specialization in brain neurogenic niche The adult mammalian brain generates neurons from the subventricular zone (SVZ). In mice, Paul et al. were able to link environmental signals with the type of neurons that are generated and showed that anatomical subspecialization occurrs in the SVZ. Neural circuits that respond to hunger or satiety enervate a subregion of the SVZ and retune the production of new olfactory neurons just from that portion of the subventricular niche. Science , this issue p. 1383