Multicenter Automatic Defibrillator Implantation Trial–Cardiac Resynchronization Therapy (MADIT‐CRT): Design and Clinical Protocol

著者: Arthur J. Moss, Mary W. Brown, David S. Cannom, James P. Daubert, Mark Estes, Elyse Foster, Henry Greenberg, William J. Hall, Steven L. Higgins, Helmut Klein, Mark A Pfeffer, David J. Wilber, Wojciech Zaręba - Annals of Noninvasive Electrocardiology 2005 被引用: 227

The planned MADIT-CRT trial is designed to determine if CRT-D will reduce the risk of mortality and HF events by approximately 25% in subjects with ischemic (NYHA class I-II) and non-ischemic (NYHA class II) cardiomyopathy, left ventricular dysfunction (EF<or=0.30), and prolonged intraventricular conduction (QRS duration>or=130 ms).