Weight Loss and Weight Regain in Usual Clinical Practice: Results From the TARGET-NASH Observational Cohort

著者: Miguel Malespin, A. Sidney Barritt, Stephanie Watkins, Cheryl Schoen, Monica A. Tincopa, Karen D. Corbin, Andrea R. Mospan, Breda Muñoz, Huy N. Trinh, Laurence Weiss, K. Rajender Reddy, Rohit Loomba, Nyingi Kemmer, Anna S. Lok - Clinical Gastroenterology and Hepatology 2021 被引用: 68

First-line treatment for nonalcoholic fatty liver disease (NAFLD) focuses on weight loss through lifestyle modifications.1,2 Weight loss ≥5% results in reduction of steatosis and weight loss ≥10% has been associated with improvement in hepatic inflammation and fibrosis.3 The incidence and sustainability of weight loss among patients with NAFLD were estimated and associating factors identified.