Deciduous autologous tooth stem cells regenerate dental pulp after implantation into injured teeth

著者: Kun Xuan, Bei Li, Hao Guo, Wei Sun, Xiaoxing Kou, Xiaoning He, Yongjie Zhang, Jin Sun, Anqi Liu, Li Liao, Shiyu Liu, Wenjia Liu, Cheng‐Hu Hu, Songtao Shi, Yan Jin - Science Translational Medicine 2018 被引用: 505

< 0.0001) compared to the apexification group. In addition, hDPSC implantation led to regeneration of dental pulp tissue containing sensory nerves. To evaluate the safety of hDPSC implantation, we followed 20 patients implanted with hDPSCs for 24 months and did not observe any adverse events. Our study suggests that hDPSCs are able to regenerate whole dental pulp and may be useful for treating tooth injuries due to trauma.