The gut microbiota influences skeletal muscle mass and function in mice

著者: Shawon Lahiri, Hye-Jin Kim, Isabel García‐Pérez, Musarrat Maisha Reza, Katherine A. Martin, Parag Kundu, Laura M. Cox, Joel Selkrig, Joram M. Posma, Hongbo Zhang, Parasuraman Padmanabhan, Catherine Moret, Balázs Gulyás, Martin J. Blaser, Johan Auwerx, Elaine Holmes, Jeremy K. Nicholson, Walter Wahli, Sven Pettersson - Science Translational Medicine 2019 被引用: 542

Treating germ-free mice with short-chain fatty acids (microbial metabolites) partly reversed skeletal muscle impairments. Our results suggest a role for the gut microbiota in regulating skeletal muscle mass and function in mice.