Prediction of permeability across intestinal cell monolayers for 219 disparate chemicals using in vitro experimental coefficients in a pH gradient system and in silico analyses by trivariate linear regressions and machine learning

Yusuke Kamiya; Asuka Omura; Riku Hayasaka; Rie Saito; Izumi Sano; Kentaro Handa; Junya Ohori; Masato Kitajima; Fumiaki Shono; Kimito Funatsu; Hiroshi Yamazaki

doi:10.1016/j.bcp.2021.114749

Prediction of permeability across intestinal cell monolayers for 219 disparate chemicals using in vitro experimental coefficients in a pH gradient system and in silico analyses by trivariate linear regressions and machine learning

著者: Yusuke Kamiya, Asuka Omura, Riku Hayasaka, Rie Saito, Izumi Sano, Kentaro Handa, Junya Ohori, Masato Kitajima, Fumiaki Shono, Kimito Funatsu, Hiroshi Yamazaki - Biochemical Pharmacology 2021 被引用: 34

Prediction of permeability across intestinal cell monolayers for 219 disparate chemicals using in vitro experimental coefficients in a pH gradient system and in silico analyses by trivariate linear regressions and machine learning | Litlas