Autologous tumor cell–derived microparticle-based targeted chemotherapy in lung cancer patients with malignant pleural effusion

著者: Mengfei Guo, Feng Wu, Guorong Hu, Lian Chen, Juanjuan Xu, Pingwei Xu, Xuan Wang, Yumei Li, Shuqing Liu, Shuai Zhang, Qi Huang, Jinshuo Fan, Zhilei Lv, Mei Zhou, Limin Duan, Tingting Liao, Guanghai Yang, Ke Tang, Bi‐Feng Liu, Xiaofei Liao, Xiao‐Nan Tao, Yang Jin - Science Translational Medicine 2019 被引用: 239

cells to release IFN-γ. Our initial experience with ATMPs-MTX in advanced lung cancer with MPE suggests that ATMPs targeting malignant cells and the immunosuppressive microenvironment may be a promising therapeutic platform for treating malignancies.