A genome-wide CRISPR-based screen identifies KAT7 as a driver of cellular senescence

著者: Wei Wang, Yuxuan Zheng, Shuhui Sun, Wei Li, Moshi Song, Qianzhao Ji, Zeming Wu, Zunpeng Liu, Yanling Fan, Feifei Liu, Jingyi Li, Concepción Rodrı́guez Esteban, Si Wang, Qi Zhou, Juan Carlos Izpisúa Belmonte, Weiqi Zhang, Jing Qu, Fuchou Tang, Guang‐Hui Liu - Science Translational Medicine 2021 被引用: 178

Inactivation of the histone acetyltransferase gene KAT7 prolongs survival in naturally aged mice and progeroid mice that age prematurely.