Chimeric Antigen Receptor Therapy

著者: Carl H. June, Michel Sadelain - New England Journal of Medicine, NEJM 2018 被引用: 2,280

Interview with Dr. Carl June on chimeric antigen receptor therapy. (09:04)Download This review addresses T-cell engineering and synthetic immunity, with a focus on producing durable remissions in patients with treatment-refractory tumors. Toxic effects of chimeric antigen receptor therapies include cytokine release syndrome and neurologic dysfunction.