Neuropeptide S receptor 1 is a nonhormonal treatment target in endometriosis

著者: Thomas T. Tapmeier, Nilüfer Rahmioğlu, Jianghai Lin, Bianca De Leo, Maik Obendorf, Muthuswamy Raveendran, Oliver M. Fischer, Cemsel Bafligil, Manman Guo, R. Alan Harris, Holger Hess‐Stumpp, Alexis Laux‐Biehlmann, Ernesto Lowy, Gerton Lunter, Jessica Malzahn, Nicholas G. Martin, Fernando O. Martínez, Sanjiv Manek, Stefanie Mesch, Grant W. Montgomery, Andrew P. Morris, Jens Nagel, Heather A. Simmons, Denise Brocklebank, Catherine A. Shang, Susan A. Treloar, Graham Wells, Christian M. Becker, Udo Oppermann, Thomas M. Zollner, Stephen Kennedy, Joseph W. Kemnitz, Jeffrey Rogers, Krina T. Zondervan - Science Translational Medicine 2021 被引用: 48

< 0.05) in a mouse model of peritoneal inflammation as well as in a mouse model of endometriosis. We conclude that the NPSR1/NPS system is a genetically validated, nonhormonal target for the treatment of endometriosis with likely increased relevance to stage III/IV disease.