Fucoxanthin alleviated myocardial ischemia and reperfusion injury through inhibition of ferroptosis via the NRF2 signaling pathway

FX stimulated NRF2 to ameliorate mitochondrial dysfunction and inhibit overloading ROS and Fe 2+ , which contribute to lipid peroxidation and thus lead to ferroptosis, alleviating MIRI.

Fucoxanthin alleviated myocardial ischemia and reperfusion injury through inhibition of ferroptosis via the NRF2 signaling pathway | Litlas