Global update on the susceptibilities of human influenza viruses to neuraminidase inhibitors and the cap-dependent endonuclease inhibitor baloxavir, 2017–2018

著者: Emi Takashita, Rod S. Daniels, Seiichiro Fujisaki, Vicki L. Gregory, Larisa V. Gubareva, Weiijuan Huang, Aeron C. Hurt, Angie Lackenby, Ha Nguyen, Dmitriy Pereyaslov, Merryn Roe, Magdi Samaan, Kanta Subbarao, Herman Tse, Dayan Wang, Hui‐Ling Yen, Wenqing Zhang, Adam Meijer - Antiviral Research 2020 被引用: 129

values were determined. The PA variant viruses showed 6-17-fold reduced susceptibility to baloxavir. Overall, in the 2017-18 period the frequency of circulating influenza viruses with reduced susceptibility to NAIs or baloxavir was low, but continued monitoring is important.