A Novel Biological Strategy for Myocardial Protection by Intracoronary Delivery of Mitochondria: Safety and Efficacy

著者: Borami Shin, Mossab Y. Saeed, Jesse J. Esch, Alvise Guariento, David Blitzer, Kamila Moskowitzova, Giovanna Ramirez-Barbieri, Arzoo Orfany, Jerusha K. Thedsanamoorthy, Douglas B. Cowan, James A. H. Inkster, Erin Snay, Steven J. Staffa, Alan B. Packard, David Zurakowski, Pedro J. del Nido, James D. McCully - JACC Basic to Translational Science 2019 被引用: 139

channels. Intracoronary mitochondrial delivery after temporary regional ischemia significantly improved myocardial function, perfusion, and infarct size. The authors concluded that intracoronary delivery of mitochondria is safe and efficacious therapy for myocardial ischemia-reperfusion injury.