Inhibition of HSP90β Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System

著者: Zu‐Guo Zheng, Xin Zhang, Xiao-Xiao Liu, Xiuxiu Jin, Lunzhi Dai, Huimin Cheng, Dan Jing, Pyone Myat Thu, Mu Zhang, Hongyang Li, Jing Zhu, Chang Liu, Bin Xue, Yu Li, Ligong Chen, Cheng Peng, Weiliang Zhu, Lin Wang, Junli Liu, Hui‐Jun Li, Ping Li, Xiaojun Xu - Theranostics 2019 被引用: 84

HSP90β plays a parolog-specific role in regulating lipid homeostasis. Compound that selectively inhibits HSP90β could be useful in the clinic for the treatment for metabolic diseases.