Global Impact of COVID-19 on Stroke Care and IV Thrombolysis

著者: Raul G. Nogueira, Muhammad M. Qureshi, Mohamad Abdalkader, Sheila Cristina Ouriques Martins, Hiroshi Yamagami, Zhongming Qiu, Ossama Yassin Mansour, Anvitha Sathya, Anna Członkowska, Georgios Tsivgoulis, Diana Aguiar de Sousa, Jelle Demeestere, Robert Mikulík, Peter Vanacker, James E. Siegler, Janika Kõrv, José Biller, Conrad W Liang, Navdeep Sangha, Alicia Zha, Alexandra L. Czap, Christine A Holmstedt, Tanya N. Turan, George Ntaios, Konark Malhotra, Ashis Tayal, Aaron Loochtan, Annemarei Ranta, Eva Mistry, Anne W. Alexandrov, David Huang, Shadi Yaghi, Eytan Raz, Sunil A. Sheth, Mahmoud Mohammaden, Michael Frankel, Eric Guemekane Bila Lamou, Hany Aref, Ahmed Elbassiouny, Farouk Hassan, Tarek Menecie, Wessam Mustafa, Hossam Shokri, Tamer Roushdy, Fred Stephen Sarfo, Tolulope Oyetunde Alabi, Babawale Arabambi, Ernest Nwazor, Taofiki Sunmonu, Kolawole Wahab, Joseph Yaria, Haytham Hussein Mohammed, Philip Adebayo, A. Riahi, Samia Ben Sassi, Lenon Gwaunza, Gift Ngwende, David Sahakyan, Aminur Rahman, Zhibing Ai, Fanghui Bai, Zhenhui Duan, Yonggang Hao, Wenguo Huang, Guangwen Li, Wei Li, Ganzhe Liu, Jun Luo, Xianjin Shang, Yi Sui, Ling Tian, Hongbin Wen, Bo Wu, Yuying Yan, Zhengzhou Yuan, Hao Zhang, Jun Zhang, Wenlong Zhao, Wenjie Zi, Thomas Leung, Chandril Chugh, Vikram Huded, Bindu Menon, Jeyaraj Pandian, PN Sylaja, Fritz Sumantri Usman, Mehdi Farhoudi, Elyar Sadeghi‐Hokmabadi, Anat Horev, Anna Reznik, Rotem Sivan Hoffmann, Nobuyuki Ohara, Nobuyuki Sakai, Daisuke Watanabe, Ryoo Yamamoto, Ryosuke Doijiri, Naoki Tokuda, Takehiro Yamada, Tadashi Terasaki, Yukako Yazawa, Takeshi Uwatoko, Tomohisa Dembo, Hisao Shimizu, Yuri Sugiura, Fumio Miyashita, Hiroki Fukuda, Kosuke Miyake, Junsuke Shimbo, Yusuke Sugimura, Yoshiki Yagita, Yohei Takenobu, Yuji Matsumaru, Satoshi Yamada, Ryuhei Kono, Takuya Kanamaru, Hidekazu Yamazaki, Manabu Sakaguchi, Kenichi Todo, Nobuaki Yamamoto, Kazutaka Sonoda, Tomoko Yoshida, Hiroyuki Hashimoto, Ichiro NAKAHARA, Аida Kondybayeva, Kamila Faizullina, Saltanat Kamenova, Murat Zhanuzakov, Jang‐Hyun Baek, Yang‐Ha Hwang, Jin Soo Lee, Si Baek Lee, Jusun Moon, Hyungjong Park, Jung Hwa Seo, Kwon–Duk Seo, Sung‐Il Sohn, Chang Jun Young, Rechdi Ahdab, Wan Asyraf Wan Zaidi, Zariah Abdul Aziz, Hamidon Basri, Law Wan Chung, Aznita Binti Ibrahim, Khairul Azmi Ibrahim, Irene Looi, Wee Yong Tan, Wan Yahya Nafisah, Stanislav Groppa, Pavel Leahu, Amal Al Hashmi, Yahia Imam, Naveed Akhtar, Maria Carissa Pineda-Franks, Christian Oliver, Д В Кандыба, Adel Alhazzani, Hosam Al-Jehani, Carol Huilian Tham, Marlie Jane Mamauag, Narayanaswamy Venketasubramanian, Chih‐Hao Chen, Sung‐Chun Tang, Anchalee Churojana, Eşref Akıl, Özlem Aykaç, Atilla Özcan Özdemi̇r, Semih Giray, Syed Hussain, Seby John, Huynh Le Vu, Anh Đức Trần, Huy Hoàng Nguyễn, Thong Nhu Pham, Thang Huy Nguyen, Trung Quoc Nguyen, Thomas Gattringer, Christian Enzinger, Monika Killer‐Oberpfalzer, Flavio Bellante, Sofie De Blauwe, Geert Vanhooren, Sylvie De Raedt, Anne Dusart, Robin Lemmens, Noémie Ligot, Matthieu Pierre Rutgers, Laetitia Yperzeele, Filip Alexiev, Teodora Sakelarova, Marina Roje Bedeković, Hrvoje Budinčević, Igor Cindrić, Zlatko Hucika, David Ozretić, Majda Seferovic Saric, František Pfeifer, Igor Karpowic, David Černík, Martin Šrámek, Miroslav Škoda, Helena Hlaváčová, Lukáš Klečka, Martin Koutny, Daniel Václavík, Ondřej Škoda, Jan Fiksa, Katerina Hanelova, Miroslava Nevšímalová, Robert Rezek, Petr Procházka, Gabriela Krejstova, Jiří Neumann, Marta Vachová, Henryk Brzezanski, David Hlinovský, Dusan Tenora, R Jura, Lubomír Jurák, Jan Novák, Aleš Novák, Zdenek Topinka, Petr Fibrich, Helena Sobolová, Ondřej Volný, Hanne Krarup Christensen, Nicolas Drenck, Helle K. Iversen, Claus Z. Simonsen, Thomas Truelsen, Troels Wienecke, Riina Vibo, Katrin Gross‐Paju, Toomas Toomsoo, Katrin Antsov, François Caparros, Charlotte Cordonnier, Maria Dan, Jean‐Marc Faucheux, Laura Mechtouff, Ömer EKER, É. Lesaine, Basile Ondzé, Roxane Peres, Fernando Pico, Michel Piotin, Raoul Pop, François Rouanet, Tatuli Gubeladze, Mirza Khinikadze, Nino Lobjanidze, Alexander Tsiskaridze, Simon Nagel, Peter A. Ringleb, Michael Rosenkranz, Holger Schmidt, Annahita Sedghi, Timo Siepmann, Kristina Szabo, Götz Thomalla, Lina Palaiodimou, Dimitrios Sagris, Odysseas Kargiotis, Péter Klivènyi, László Szapáry, Gábor Tárkányi, Alessandro Adami, Fabio Bandini, Paolo Calabresi, Giovanni Frisullo, Leonardo Renieri, Davide Sangalli, Anne Pirson, Maarten Uyttenboogaart, Ido R. van den Wijngaard, Espen Saxhaug Kristoffersen, Waldemar Brola, Małgorzata Fudala, Ewa Horoch-Łyszczarek, Michał Karliński, Radosław Kaźmierski, Paweł Kram, Marcin Rogoziewicz, Rafał Kaczorowski, Piotr Luchowski, Halina Sienkiewicz‐Jarosz, Piotr Sobolewski, Waldemar Fryze, Anna Wiśniewska, M Wiszniewska, Patrícia Ferreira, Paulo Ferreira, Luísa Fonseca, João Pedro Marto, Teresa M. V. D. Pinho e Melo, Ana Paiva Nunes, Miguel Rodrigues, Vítor Tedim Cruz, Cristian Falup‐Pecurariu, Georgi Krastev, Miroslav Mako, María Alonso de Leciñana, Juan F. Arenillas, Óscar Ayo‐Martín, Antonio Culebras, Exuperio Díez‐Tejedor, Joan Montaner, Soledad Pérez-Sánchez, Miguel Ángel Tola-Arribas, Alejandro Rodríguez Vásquez, Michael Mayza, Gianmarco Bernava, Alex Brehm, Paolo Machi, Urs Fischer, Jan Gralla, Patrik Michel, Marios‐Nikos Psychogios, Davide Strambo, Soma Banerjee, Kailash Krishnan, Joseph Kwan, Asif Butt, Luciana Catanese, Andrew M. Demchuk, Thalia S. Field, Jennifer Haynes, Michael D. Hill, Houman Khosravani, Ariane Mackey, Aleksandra Pikula, Gustavo Saposnik, Courtney Anne Scott, Ashkan Shoamanesh, Ashfaq Shuaib, Samuel Yip, Miguel A. Barboza, José Domingo Barrientos, Ligia Ibeth Portillo Rivera, Fernando Góngora‐Rivera, Nelson Novarro, Anmylene Blanco, Michael Abraham, Diana Alsbrook, Dorothea Altschul, Anthony J. Alvarado-Ortiz, Ivo Bach, Aamir Badruddin, Nobl Barazangi, Charmaine Brereton, Alicia C. Castonguay, Seemant Chaturvedi, Saqib Chaudry, Hana Choe, Jae Hyung Choi, Sushrut Dharmadhikari, Kinjal Desai, Thomas Devlin, Vinodh T Doss, Randall C. Edgell, Mark R. Etherton, Mudassir Farooqui, Don Frei, Dheeraj Gandhi, Mikayel Grigoryan, Rishi Gupta, Ameer E Hassan, Johanna Helenius, Artem Kaliaev, Ritesh Kaushal, Priyank Khandelwal, Ayaz Khawaja, Naïm Khoury, Benny S. Kim, Dawn Kleindorfer, Feliks Koyfman, V Lee, Lester Y. Leung, Guillermo Linares, Italo Linfante, Helmi L. Lutsep, Lisa Macdougall, Shailesh Male, Amer M. Malik, Hesham Masoud, Molly McDermott, Brijesh Mehta, Jiangyong Min, Manoj Mittal, Jane G. Morris, Sumeet Multani, Fadi Nahab, Krishna Nalleballe, Claude Nguyen, Roberta Novakovic‐White, Santiago Ortega‐Gutiérrez, Rahul Rahangdale, Pankajavalli Ramakrishnan, José R. Romero, Natalia S. Rost, Aaron Rothstein, Sean Ruland, Ruchir Shah, Malveeka Sharma, Brian Silver, Marc Simmons, Abhishek Singh, Amy Starosciak, Sheryl Strasser, Viktor Szeder, Mohamed Teleb, Jenny P. Tsai, Barbara Voetsch, Oscar Balaguera, Virginia Pujol Lereis, Adriana Luraschi, Marcele Schettini Almeida, Fabrício Bruno Cardoso, Adriana Bastos Conforto, Leonardo Deus-Silva, Luidia Varrone Giacomini, Fabrício Oliveira Lima, Alexandre Luiz Longo, Pedro Magalhães, Rodrigo Targa Martins, Francisco Mont’Alverne, Daissy Liliana Mora Cuervo, Letícia C. Rebello, Lenise Valler, Viviane Flumignan Zétola, Pablo M. Lavados, Víctor Navia, Verónica V. Olavarría, Juan Manuel Toro, Pablo Felipe Ricardo Amaya, Hernán Bayona, Ángel Corredor, Carlos Eduardo Rivera Ordoñez, Diana Katherine Mantilla Barbosa, Osvaldo Lara, Mauricio R. Patiño, Luis Escobar, Donoband Edson Dejesus Melgarejo Fariña, Analia Cardozo Villamayor, Adolfo Javier Zelaya Zarza, Danny M. Barrientos-Imán, Liliana Rodríguez Kadota, Bruce Campbell, Graeme J. Hankey, Casey Hair, Timothy Kleinig, Alice Ma, Rodrigo Tomazini Martins, Ramesh Sahathevan, Vincent Thijs, Daniel E. Salazar, Teddy Y. Wu, Diogo C Haussen, David S. Liebeskind, Dileep R. Yavagal, Tudor G. Jovin, Osama O. Zaidat, Thanh N. Nguyen, on behalf of the SVIN COVID-19 Global Stroke Registry - Neurology 2021 被引用: 154

OBJECTIVE: To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods. METHODS: We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases. RESULTS: < 0.0001) was noted over the 2 later (May, June) vs the 2 earlier (March, April) pandemic months. There was a 1.48% stroke rate across 119,967 COVID-19 hospitalizations. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was noted in 3.3% (1,722/52,026) of all stroke admissions. CONCLUSIONS: The COVID-19 pandemic was associated with a global decline in the volume of stroke hospitalizations, IVT, and interfacility IVT transfers. Primary stroke centers and centers with higher COVID-19 inpatient volumes experienced steeper declines. Recovery of stroke hospitalization was noted in the later pandemic months.