Abnormal mitochondrial iron metabolism damages alveolar type II epithelial cells involved in bleomycin-induced pulmonary fibrosis

著者: Min Shao, Haipeng Cheng, Xiaohong Li, Yujia Qiu, Yunna Zhang, Yanfen Chang, Jiafeng Fu, Mengxia Shen, Xinxin Xu, Dandan Feng, Yang Han, Shaojie Yue, Yan Zhou, Ziqiang Luo - Theranostics 2024 被引用: 40

Our findings highlight the unexplored roles, mechanisms, and regulatory approaches of abnormal mitochondrial iron metabolism of AECII in pulmonary fibrosis. Therefore, this study deepens the understanding of the mechanisms underlying pulmonary fibrosis and offers a promising strategy for developing effective therapeutic interventions using the EP4 receptor activator.