Multifunctional Antimicrobial Nanofiber Dressings Containing ε-Polylysine for the Eradication of Bacterial Bioburden and Promotion of Wound Healing in Critically Colonized Wounds

著者: Venkatesh Mayandi, Alvin Wen Choong Chua, Chetna Dhand, Fui Ping Lim, Thet Tun Aung, Harini Sriram, Neeraj Dwivedi, Mercy Halleluyah Periayah, Sreepathy Sridhar, Mobashar Hussain Urf Turabe Fazil, Eunice Tze Leng Goh, Gorka Orive, Roger W. Beuerman, Timothy Barkham, Xian Jun Loh, Zhao‐Xun Liang, Veluchamy A. Barathi, Seeram Ramakrishna, Si Jack Chong, Navin Kumar Verma, Rajamani Lakshminarayanan - ACS Applied Materials & Interfaces 2020 被引用: 112

colonized partial thickness burns, NFDs decreased bacterial bioburden and promoted wound closure and re-epithelialization. NFDs displayed superior clinical outcome than standard-of-care silver dressings. The excellent biocompatibility and antimicrobial efficacy of the newly developed dressings in pre-clinical models demonstrate its potential for clinical use to manage infected wounds without compromising tissue regeneration.