Functionalised staple linkages for modulating the cellular activity of stapled peptides

著者: Yu Heng Lau, Peterson de Andrade, S.T. Quah, Maxim Rossmann, Luca Laraia, Niklas Sköld, Tze Jing Sum, Pamela J. E. Rowling, Thomas L. Joseph, Chandra Verma, Marko Hyvönen, Laura S. Itzhaki, Ashok R. Venkitaraman, Christopher J. Brown, David P. Lane, David R. Spring - Chemical Science 2014 被引用: 214

A divergent synthetic strategy for generating helical p53 peptides bearing functionalised staple linkages, allowing for efficient optimisation of cellular activity.