ATF6 aggravates acinar cell apoptosis and injury by regulating p53/AIFM2 transcription in Severe Acute Pancreatitis

著者: Jiehui Tan, Rong-chang Cao, Lei Zhou, Zhitao Zhou, Huoji Chen, Jia Xu, Xuemei Chen, Yang-chen Jin, Jiayu Lin, Jun-ling Zeng, Shu-Ji Li, Min Luo, Guodong Hu, Xiao-Bing Yang, Jin Jin, Guowei Zhang - Theranostics 2020 被引用: 112

These results reveal that ATF6/p53/AIFM2 pathway plays a critical role in acinar apoptosis during SAP progression, highlighting novel therapeutic target molecules for SAP.