Bacteriophage Treatment Rescues Mice Infected with Multidrug-Resistant Klebsiella pneumoniae ST258

著者: Shayla Hesse, Natalia Małachowa, Adeline R. Porter, Brett A. Freedman, Scott D. Kobayashi, Donald J. Gardner, Dana Scott, Sankar Adhya, Frank R. DeLeo - mBio 2021 被引用: 93

(sequence type 258 [ST258]) bacteremia in a murine infection model. Moreover, we compare outcomes among three distinct phage treatment groups and identify potential correlates of therapeutic phage efficacy. These findings constitute an important first step toward optimizing and assessing phage therapy's potential for the treatment of severe ST258 infection in humans.