PSCA and MUC1 in non-small-cell lung cancer as targets of chimeric antigen receptor T cells

著者: Xinru Wei, Yunxin Lai, Jin Li, Le Qin, Youdi Xu, Ruocong Zhao, Baiheng Li, Simiao Lin, Suna Wang, Qiting Wu, Qiubin Liang, Muyun Peng, Fenglei Yu, Yangqiu Li, Xuchao Zhang, Yi‐Long Wu, Pentao Liu, Duanqing Pei, Yao Yao, Peng Li - OncoImmunology 2017 被引用: 139

tumors when combined with MUC1-targeting CAR T cells. Taken together, our studies demonstrate that PSCA and MUC1 are both promising CAR T cell targets in NSCLC and that the combinatorial targeting of these antigens could further enhance the antitumor efficacy of CAR T cells.