Preconditioned extracellular vesicles from hypoxic microglia reduce poststroke AQP4 depolarization, disturbed cerebrospinal fluid flow, astrogliosis, and neuroinflammation

著者: Wenqiang Xin, Yongli Pan, Wei Wei, Lars Tatenhorst, Irina Graf, Aurel Popa‐Wagner, Stefan T. Gerner, Sabine Huber, Ertuğrul Kılıç, Dirk M. Hermann, Mathias Bähr, Hagen B. Huttner, Thorsten R. Doeppner - Theranostics 2023 被引用: 64

These findings show that hypoxic microglia may participate in protecting against stroke-induced brain damage by regulating poststroke inflammation, astrogliosis, AQP4 depolarization, and CSF flow due to EV release.