Mutation Frequencies and Antibiotic Resistance

著者: José Luis Martínez, Fernando Baquero - Antimicrobial Agents and Chemotherapy 2000 被引用: 703

Antibiotic resistance can be achieved by horizontal acquisition of resistance genes (carried by plasmids or transposons), by recombination of foreign DNA into the chromosome, or by mutations in different chromosomal loci ([15][1]). In studies of molecular evolutionary biology, the term mutation rate