Reperfusion therapies and in-hospital outcomes for ST-elevation myocardial infarction in Europe: the ACVC-EAPCI EORP STEMI Registry of the European Society of Cardiology

著者: Uwe Zeymer, Peter Ludman, Nicolas Danchin, Petr Kala, Cécile Laroche, Masoumeh Sadeghi, Roberto Caporale, Sameh Mohamed Shaheen, Jacek Legutko, Zaza Iakobsishvili, Khalid F. AlHabib, Zuzana Moťovská, Martin Studenčan, Jorge Mimoso, Dávid Becker, Dimitrios Alexopoulos, Zviad Kereseselidze, Siniša Stojković, Parounak Zelveian, Artan Goda, Erkin М Мirrakhimov, Gani Bajraktari, Hasan Al-Farhan, Pranas Šerpytis, Bent Raungaard, Toomas Marandi, Alice May Moore, Martin Quinn, Pasi Paavo Karjalainen, Gabriel Tatu-Chitolu, Chris P Gale, Aldo P Maggioni, Franz Weidinger, the ACVC EAPCI EORP ACS STEMI investigators group of the ESC, Franz Weidinger, Uwe Zeymer, Nicolas Danchin, Peter Ludman, Peter Sinnaeve, Petr Kala, Roberto Ferrari, Aldo P Maggioni, Artan Goda, Parounak Zelveian, Franz Weidinger, Kiril Karamfilov, Zuzana Moťovská, Uwe Zeymer, Bent Raungaard, Toomas Marandi, Sameh Mohamed Shaheen, Rosa-María Lidón, Pasi Paavo Karjalainen, Zviad Kereselidze, Dimitrios Alexopoulos, Dávid Becker, Martin Quinn, Zaza Iakobishvili, Hasan Al-Farhan, Masoumeh Sadeghi, Roberto Caporale, Erkin М Мirrakhimov, Pranas Šerpytis, Andrejs Ērglis, Saško Kedev, Alice May Moore, Dariusz Dudek, Jacek Legutko, Jorge Mimoso, Gabriel Tatu-Chiţoiu, Siniša Stojković, Е. V. Shlyakhto, Khalid F. AlHabib, Matjaž Bunc, Martin Studenčan, Mohamed Sami Mourali, Gani Bajraktari, Marème Konté, Florian Larras, Elin Folkesson Lefrancq, Souad Mekhaldi, Cécile Laroche, Aldo P Maggioni, A Goda, Naltin Shuka, E Pavli, E Tafaj, Taulant Gishto, Alban Dibra, Arvi Duka, A Gjana, Aleksandra S. Kristo, G Knuti, Aurel Demiraj, E Dado, Endri Hasimi, Leonard Simoni, M Siqeca, Hamayak Sisakian, Hamlet Hayrapetyan, S. A. Markos’yan, L Galustyan, N Arustamyan, H Kzhdryan, Sergey Pepoyan, A Zirkik, Dirk von Lewinski, S Paetzold, I Kienzl, K Mátyás, Thomas Neunteufl, Mariam Nikfardjam, U Neuhold, A Mihalcz, F Glaser, Clemens Steinwender, Christian Reiter, Michael Grund, Dragan Hrnčić, Uta C. Hoppe, Matthias Hammerer, Lynne Hinterbuchner, Christian Hengstenberg, Georg Delle Karth, Iréne Lang, Franz Weidinger, W. Winkler, Matthias Hasun, Johannes Kästner, C. Havel, Michael Derntl, G Oberegger, Johannes Hajos, Christopher Adlbrecht, T. Publig, M-C Leitgeb, R Wilfing, Peter Jirak, Carolyn Y. Ho, L Puskas, Lore Schrutka, Jindřich Špinar, Jiří Pařenica, Ota Hlinomaz, V Fendrychova, Jiří Seménka, J Sikora, Jan Sitar, Ladislav Groch, M Rezek, Martin Novák, P Kramarikova, J Stasek, J Dušek, Petr Zdráhal, Rostislav Polášek, Jiří Karásek, Jiří Seiner, N Sukova, Ivo Varvařovský, Tomáš Lazarák, Vojtěch Novotný, Jan Matějka, Richard Rokyta, Štefan Volovár, Jan Bělohlávek, Zuzana Moťovská, Michal Širanec, M Kamenik, R Kralik, Bent Raungaard, Jan Ravkilde, Svend Eggert Jensen, Anton Boel Villadsen, K Villefrance, Charlotte Schmidt Skov, Michael Mæng, K Moeller, Hosam Hasan‐Ali, Tarek Ahmed, M Hassan, Ahmed ElGuindy, M Farouk Ismail, A Ibrahim Abd El-Aal, Ahmed Gaafar, Hasnita Hassan, Mohammad Shafie, M Elkhouly, Ahmed Bendary, M Darwish, Yesuf Ahmed, Osama Ahmed Amin, A AbdElHakim, K Abosaif, Hossam Kandil, M A G Galal, E E El Hefny, Mazen El Sayed, K Aly, Moustafa Mokarrab, Mohammed Osman, Magdy Abdelhamid, S Mantawy, Mohammad Ridhuan Mohd Ali, S D Kaky, Viviane Khalil, Mahmoud Saraya, Ahmed Talaat, M Nabil, W M Mounir, Karim D. Mahmoud, A Aransa, Ghada Kazamel, S Anwar, Ahmed Al‐Habbaa, M Abd el Monem, Ahmed Ismael, M Amin Abu-Sheaishaa, M M Abd Rabou, T M A Hammouda, M Moaaz, Khaled Elkhashab, Tamer Mosaad Ragab, A Rashwan, A Rmdan, Gomaa Abdelrazek, Hassan Ebeid, Haytham Soliman Ghareeb, Nabil Farag, Mohamed Ahmed Zaki, M Seleem, A Torki, Mahmoud Youssef, N A AlLah Nasser, A Rafaat, H Selim, M M Makram, M. A. Khayyal, K Malasi, Ashraf Madkour, M Kolib, Haitham Alkady, H Nagah, M Yossef, A Wafa, E Mahfouz, G Faheem, M Magdy Moris, Ahmed Ragab, Mohammed Ghazal, A Mabrouk, M Hassan, Magdy Mohamed Elmasry, Mohamed Naseem, Sameh Samir, Toomas Marandi, J Reinmets, M Allvee, Aet Saar, Tiia Ainla, A Vaide, M Kisseljova, U Pakosta, Jaan Eha, K Lotamois, Jussi Sia, Juhani Myllymäki, T Pinola, Pasi P. Karjalainen, Tuomas Paana, Jussi Mikkelsson, M Ampio, J Tsivilasvili, P Zurab, Zviad Kereselidze, Rusudan Agladze, A Melia, D Gogoberidze, N Khubua, L Totladze, I Metreveli, A Chikovani, Ingo Eitel, Janine Pöss, M. Werner, A Constantz, C Ahrens, Uwe Zeymer, H Tolksdorf, S Klinger, S. Sack, Tobias Heer, J. Lekakis, John Kanakakis, Iosif Xenogiannis, K Ermidou, Nikolaos Makris, Argyrios Ntalianis, Fotios K. Katsaros, E Revi, K Kafkala, E Mihelakis, George F. Diakakis, K Grammatikopoulos, D Voutsinos, Dimitrios Alexopoulos, Ioanna Xanthopoulou, Virginia Mplani, Stefanos Foussas, Nikolaos A. Papakonstantinou, Nikolaos Patsourakos, A Dimopoulos, A Derventzis, Kyriacos A. Athanasiou, Vasileios Vassilikos, Christodoulos Papadopoulos, Stergios Tzikas, Ioannis Vogiatzis, A Datsios, I Galitsianos, Konstantinos Koutsampasopoulos, Savvas Grigoriadis, A Douras, Nour-Eddine Baka, S Spathis, T Kyrlidis, H. Hatzinikolaou, Róbert Gábor Kiss, Dávid Becker, Fanni Nowotta, Kálmán Tóth, Sofia Szabo, C Lakatos, Zoltán Jambrik, J Ruzsa, Zoltán Ruzsa, Szilárd Róna, Jean C. Toth, A Vargane Kosik, Kálmán Tóth, Gergely Nagy, Z Ondrejkó, Z Körömi, Balázs Botos, M Pourmoghadas, Amir Mohammad Salehi, Gholamreza Massoumi, Masoumeh Sadeghi, Abbas Soleimani, Nizal Sarrafzadegan, H. Roohafza, Maedeh Azarm, Arash Mirmohammadsadeghi, D Rajabi, Yousef Rahmani, Soraya Siabani, Farid Najafi, Behrooz Hamzeh, Hosein Karim, Hossein Siabani, Nawzad Saleh, H Charehjoo, L Zamzam, G Al-Temimi, Hasan Ali Farhan, A Al-Yassin, Amin A. Mohammad, A Ridha, G Al-Saedi, N Atabi, O Sabbar, Shazil Mahmood, Zainab Atiyah Dakhil, Israa Fadhil Yaseen, M Almyahi, H Alkenzawi, Tahsin Al-Kinani, A Alyacopy, Peter Kearney, K.M. Twomey, Zaza Iakobishvili, N Shlomo, Roy Beigel, Pasquale Caldarola, David Rutigliano, L Sublimi Saponetti, Nicola Locuratolo, V Palumbo, Marino Scherillo, Dario Formigli, Paolo Canova, Giuseppe Musumeci, F Roncali, Marco Metra, Carlo Lombardi, Emanuele Visco, L Rossi, Luigi Meloni, Roberta Montisci, V Pippia, Maria Francesca Marchetti, Michela Congia, Cristina Cacace, G. De Luca, Giuseppe Boscarelli, C Indolfi, Giuseppe Ambrosio, Annalisa Mongiardo, Carmen Spaccarotella, Salvatore De Rosa, Giovanni Canino, Claudia Critelli, Roberto Caporale, Daniela Chiappetta, F Battista, Domenico Gabrielli, Alessandro Marziali, Paola Bernabò, Alessandro Navazio, E Guerri, Francesco Manca, M Gobbi, Giuseppe Oreto, Giuseppe Andò, Scipione Carerj, Francesco Saporito, Michele Cimmino, Fausto Rigo, Guerrino Zuin, B Tuccillo, Fortunato Scotto di Uccio, L Irace, Giovanni Lorenzoni, Ivan Meloni, Pierluigi Merella, Giovanni Polizzi, Roberto del Pino, Mario Marzilli, Doralisa Morrone, Paolo Caravelli, Enrico Orsini, S Mosa, Giancarlo Piovaccari, Andrea Santarelli, Caterina Cavazza, Francesco Romeo, Francesco Fedele, Massimo Mancone, Martina Straito, Nicolò Salvi, Paola Scarparo, Paolo Severino, Cinzia Razzini, Giulia Massaro, Alessandra Cinque, Carlo Gaudio, Francesco Barillà, Concetta Torromeo, Luigina Porco, M Mei, Raffaele Iorio, Daniele Nassiacos, B Barco, Gianfranco Sinagra, Luigi Falco, Luigi Priolo, Andrea Perkan, M Strana, Gani Bajraktari, L Percuku, G Berisha, B Mziu, Medet Beishenkulov, Tamila Abdurashidova, A. K. Toktosunova, K. R. Kaliev, Pranas Šerpytis, Rokas Šerpytis, Eglė Butkutė, Mindaugas Lizaitis, M Broslavskyte, Robert G. Xuereb, Alice Moore, Matthew Mercieca Balbi, E Paris, L Buttigieg, W Musiał, Sławomir Dobrzycki, Artur Dubicki, E Kazimierczyk, Agnieszka Tycińska, Wojciech Wojakowski, Barbara Kalańska-Łukasik, Andrzej Ochała, Wojciech Wańha, Sebastian Dworowy, Janusz Sielski, Marianna Janion, Agnieszka Janion−Sadowska, Dariusz Dudek, Joanna Wojtasik-Bakalarz, Leszek Bryniarski, Jan Z. Peruga, M Jonczyk, Łukasz Jankowski, Artur Klecha, Jacek Legutko, Joanna Michałowska, Michał Brzeziński, T Kozmik, Tomasz Kowalczyk, J Adamczuk, M Maliszewski, P Kuziemka, Pedro Plaza, A Jaros, A Pawelec, J Sledz, Stanisław Bartuś, Witold Żmuda, M Bogusz, M Wisnicki, Grzegorz Szastak, Maria Adamczyk, Marcin Suska, Piotr Czunko, Grzegorz Opolski, Janusz Kochman, Mariusz Tomaniak, Sylwia Miernik, Katarzyna Paczwa, Adam Witkowski, Maksymilian P. Opolski, Adam D. Staruch, Zbigniew Kalarus, Grzegorz Honisz, Grzegorz Mencel, Marcin Świerad, Tomasz Podolecki, J Marqués, Pedro Azevedo, M A Pereira, António Gaspar, Sílvia Monteiro, Francisco Gonçalves, Luís Leite, Jorge Mimoso, Walter Santos, J.A. Amado, D. Pereira, B Silva, G Caires, M Neto, R. Rodrigues, A Correia, D Freitas, André P. Lourenço, Felipe Ferreira, F Sousa, João Português, Luís Calvo, F Almeida, M Alves, A Silva, Rui Caria, Filipe Seixo, Cristian Militaru, E Ionica, Gabriel Tatu-Chiţoiu, Octavian Istrătoaie, Maria Florescu, E Lipnitckaia, О. А. Осипова, S. L. Konstantinov, В Букатов, T Vinokur, Е. И. Егорова, E Nefedova, S Levashov, А. В. Горбунова, M Redkina, N Karaulovskaya, F Bijieva, N Babich, О Ю Смирнова, R Filyanin, S Eseva, A Kutluev, A Chlopenova, A Shtanko, E Kuppar, E Shaekhmurzina, М. К. Ибрагимова, M Mullahmetova, M Chepisova, M Kuzminykh, M Betkaraeva, А. М. Намитоков, Н. Р. Хасанов, L. V. Baleeva, Z Galeeva, F Magamedkerimova, E Ivantsov, Е. В. Тавлуева, А. М. Кочергина, D. Yu. Sedykh, Elena Kosmachova, В. В. Скибицкий, Н. В. Породенко, А. М. Намитоков, K Litovka, E Ulbasheva, S Niculina, Miriam Petrová, E Harkov, N Tsybulskaya, A Lobanova, А. А. Чернова, A Kuskaeva, A Kuskaev, М Я Руда, D. A. Zateyshchikov, M Gilarov, Е. В. Константинова, O. N. Koroleva, A Averkova, N. S. Zhukova, D Kalimullin, N. Yu. Borovkova, A Tokareva, M. V. Buyanova, Л. А. Хаишева, А. А. Пироженко, T Novikova, A. N. Yakovlev, T. V. Tyurina, K Lapshin, Надежда Морошкина, М.А. Киселева, S Fedorova, L Krylova, D. V. Duplyakov, Y Semenova, А. М. Русина, V. V. Ryabov, А. Г. Сыркина, S Demianov, Olga Reitblat, A Artemchuk, Е. В. Ефремова, Е. Р. Макеева, М. В. Мензоров, А М Шутов, N. I. Klimova, Ю Л Шевченко, O Elistratova, O Kostyuckova, Rinat Islamov, V Budyak, E. Yu. Ponomareva, U Ullah Jan, Abdullah Alshehri, E Sedky, Z Alsihati, Layth Mimish, A Selem, Asif Malik, O Majeed, Issam Altnji, Mohammed Alshehri, A Aref, Khalid F. AlHabib, M AlDosary, Shawky Tayel, M Abd AlRahman, Kazi Nur Asfina, Gamal Hussein, M Butt, N Markovic Nikolic, Slobodan Obradović, Nemanja Djenic, M Brajović, Aleksandar Davidović, Radoslav Romanović, V Novakovic, Milica Dekleva, M Spasic, Boris Džudović, Zoran Jović, Dane Cvijanović, S Veljković, Igor Ivanov, Milenko Čanković, Milana Jaraković, M Kovacevic, Miloš Trajković, Vladimir Mitov, Albino Jović, Martin Hudec, M Gombasky, J Sumbal, Allan Böhm, Е. И. Баранова, F Kovar, Matej Samoš, J Podoba, Peter Kurray, T Obona, A Remenarikova, Boris Kollárik, D Verebova, G Kardosova, Martin Studenčan, D Alusik, J Mačáková, M Kozlej, Antoni Bayés‐Genís, Alessandro Sionís, C Garcia Garcia, R-M Lidon, A Duran Cambra, Carles Salvador, F Rueda Sobella, J. Roselló, Montserrat Vilà, Teresa Oliveras Vilà, Marc Ferrer Massot, Jordi Bañeras, Iñaki Lekuona, G. Zugazabeitia, Antonio Fernández‐Ortíz, Ana Viana Tejedor, C Ferrera, Vicente Álvarez, Óscar Dı́az-Castro, Rosa María Agra-Bermejo, Cristina González-Cambeiro, Eva González‐Babarro, J Domingo-Del Valle, N. Royuela, V. Burgos, A. Canteli, C Castrillo, M. Cobo, M Ruiz, Emad Abu‐Assi, J M Garcia Acuna - European Heart Journal 2021 被引用: 80

AIMS: The aim of this study was to determine the contemporary use of reperfusion therapy in the European Society of Cardiology (ESC) member and affiliated countries and adherence to ESC clinical practice guidelines in patients with ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS: Prospective cohort (EURObservational Research Programme STEMI Registry) of hospitalized STEMI patients with symptom onset <24 h in 196 centres across 29 countries. A total of 11 462 patients were enrolled, for whom primary percutaneous coronary intervention (PCI) (total cohort frequency: 72.2%, country frequency range 0-100%), fibrinolysis (18.8%; 0-100%), and no reperfusion therapy (9.0%; 0-75%) were performed. Corresponding in-hospital mortality rates from any cause were 3.1%, 4.4%, and 14.1% and overall mortality was 4.4% (country range 2.5-5.9%). Achievement of quality indicators for reperfusion was reported for 92.7% (region range 84.8-97.5%) for the performance of reperfusion therapy of all patients with STEMI <12 h and 54.4% (region range 37.1-70.1%) for timely reperfusion. CONCLUSIONS: The use of reperfusion therapy for STEMI in the ESC member and affiliated countries was high. Primary PCI was the most frequently used treatment and associated total in-hospital mortality was below 5%. However, there was geographic variation in the use of primary PCI, which was associated with differences in in-hospital mortality.