Role of Extracellular DNA in Initial Bacterial Adhesion and Surface Aggregation

著者: Theerthankar Das, Prashant K. Sharma, Henk J. Busscher, Henny C. van der Mei, Bastiaan P. Krom - Applied and Environmental Microbiology 2010 被引用: 327

Extracellular DNA (eDNA) is an important component of the biofilm matrix. We show that removal of eDNA from Gram-positive bacteria reduces initial adhesion to and aggregation of bacteria on surfaces. Thermodynamic analyses indicated that eDNA introduces favorable acid-base interactions, explaining the effect of eDNA on aggregation and adhesion to the surface.