Targeting of a Photosensitizer to the Mitochondrion Enhances the Potency of Photodynamic Therapy

著者: Sakkarapalayam M. Mahalingam, Josue D. Ordaz, Philip S. Low - ACS Omega 2018 被引用: 118

release. We conclude that triphenylphosphine has a better mitochondria-targeting moiety than guanidinium or bis-guanidinium and those PDT photosensitizers with improved cytotoxicities can be prepared by conjugating a mitochondria-targeting moiety to the desired photosensitizer.